SCHEMBL2297983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1612079	0.79	MAOA (0.51)	NPC1RAB9APOLBALDH1A1KDM4E
	SCHEMBL10664901	0.72	ALDH1A1 (0.38)	NPC1RAB9AMAPTPOLBBAZ2B
	SCHEMBL11927529	0.72	TYMS (0.42)	MAPTALDH1A1KDM4EMAOAHPGD
	SCHEMBL2300251	0.71	HDAC1 (0.46)	NPC1RAB9AKMT2AMEN1
	SCHEMBL9248385	0.71	ACHE (0.46)	MAPTALDH1A1KDM4EL3MBTL1MAOA
	SCHEMBL8789258	0.71	BAZ2B (0.37)	NPC1RAB9AMAPTPOLBBAZ2B
	SCHEMBL31607338	0.70	ALDH1A1 (0.39)	NPC1RAB9AMAPTPOLBBAZ2B
	SCHEMBL1337358	0.70	BAZ2B (0.49)	NPC1RAB9AMAPTBAZ2BALDH1A1
	SCHEMBL4877329	0.70	MAOA (0.49)	NPC1RAB9ABAZ2BALDH1A1KDM4E
	SCHEMBL18840537	0.69	NPC1 (0.46)	NPC1RAB9AMAPTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.