Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21220004 | 0.88 | NPC1 (0.43) | PTGESHCAR3NPC1LMNAMAPT | |
| SCHEMBL21220014 | 0.84 | LMNA (0.38) | HCAR3NPC1LMNAMAPTATM | |
| SCHEMBL21220008 | 0.76 | ALDH1A1 (0.41) | HCAR3LMNAMAPTATML3MBTL1 | |
| SCHEMBL21228671 | 0.76 | LMNA (0.36) | HCAR3NPC1LMNAMAPTATM | |
| SCHEMBL21228640 | 0.74 | LMNA (0.35) | HCAR3NPC1LMNAMAPTATM | |
| SCHEMBL21228630 | 0.73 | ABCB11 (0.34) | PTGESHCAR3LMNAGAATSHR | |
| SCHEMBL21220022 | 0.72 | LMNA (0.40) | LMNAMAPTATML3MBTL1GAA | |
| SCHEMBL21220009 | 0.71 | PTGES (0.46) | PTGESLMNAGAATSHR | |
| SCHEMBL21220012 | 0.71 | LMNA (0.38) | HCAR3NPC1LMNAMAPTATM | |
| SCHEMBL21228643 | 0.69 | ALDH1A1 (0.39) | HCAR3LMNAMAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927245-B2 | Non-migratory internal plasticizers attached to a pendant covalent linkage | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-23 | — | — | US | disclosed |