Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2305006 | 0.97 | PDIA6 (0.40) | CA12CA1CA2CA9TSHR | |
| SCHEMBL2305813 | 0.90 | GPR84 (0.38) | TSHRXDHGPR84PABPC1MAPK1 | |
| SCHEMBL2301170 | 0.87 | CA2 (0.40) | CA12CA1CA2CA9TSHR | |
| SCHEMBL2301153 | 0.86 | CA1 (0.43) | CA12CA1CA2CA9CA7 | |
| SCHEMBL2300334 | 0.86 | MAPT (0.35) | CA12CA1CA2CA9CA7 | |
| SCHEMBL2301951 | 0.86 | CA2 (0.41) | CA12CA1CA2CA9GPR84 | |
| SCHEMBL2300359 | 0.85 | CA2 (0.41) | CA12CA1CA2CA9TSHR | |
| SCHEMBL2237662 | 0.82 | PTGS2 (0.37) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL2300517 | 0.81 | PTGS2 (0.41) | CA12CA1CA2CA9CA7 | |
| SCHEMBL2302962 | 0.81 | CTDSP1 (0.40) | TSHRRECQLALDH1A1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536693-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | Université Laval (CA) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011100840-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | UNIVERSITé LAVAL (CA) | 2011-08-25 | — | — | WO | disclosed |