Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 3/20 | 0.38 |
| ▸ | UBA3 | Q8TBC4 | 3/20 | 0.38 |
| ▸ | AHCY | P23526 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.32 |
| ▸ | ATG7 | O95352 | 1/20 | 0.32 |
| ▸ | UBA7 | P41226 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23080204 | 0.81 | P2RX7 (0.41) | NAE1UBA3AHCYADORA2AADORA1 | |
| SCHEMBL23080228 | 0.78 | NAE1 (0.37) | NAE1UBA3AHCYADORA2AADORA1 | |
| SCHEMBL21283410 | 0.77 | TMIGD3 (0.52) | ADORA2AADORA1PDE4APDE4BPDE4C | |
| SCHEMBL18630514 | 0.77 | NAE1 (0.58) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL23080267 | 0.76 | NAE1 (0.39) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL20008056 | 0.76 | NAE1 (0.48) | NAE1UBA3PDE4APDE4BPDE4C | |
| SCHEMBL23080289 | 0.75 | NAE1 (0.41) | NAE1UBA3ADORA2AADORA1PDE4A | |
| SCHEMBL18631311 | 0.73 | ADORA3 (0.41) | NAE1UBA3ADORA2AADORA1PDE4A | |
| SCHEMBL20008118 | 0.72 | AHCY (0.33) | NAE1UBA3AHCYADORA2AADORA1 | |
| SCHEMBL12652415 | 0.68 | BCHE (0.45) | NAE1UBA3ALDH1A1UBA6ATG7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070798-A1 | Inhibitors of E1 activating enzymes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070798-A1 | Inhibitors of E1 activating enzymes | ECE1, RNASE1, RCE1 | NAE1 41/4885UBA3 12/4885AHCY 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.