Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 1/20 | 0.41 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | ATG7 | O95352 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008037 | 0.83 | ATG7 (0.40) | NAE1UBA3ATG7CA1CA2 | |
| SCHEMBL23080204 | 0.77 | P2RX7 (0.41) | NAE1UBA3ADORA2APDE4APDE4B | |
| SCHEMBL21283410 | 0.76 | TMIGD3 (0.52) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23080250 | 0.75 | NAE1 (0.38) | NAE1UBA3ADORA2AATG7PDE4A | |
| SCHEMBL23080223 | 0.74 | ATG7 (0.40) | NAE1UBA3ATG7ALDH1A1CA1 | |
| SCHEMBL23080228 | 0.73 | NAE1 (0.37) | NAE1UBA3ADORA2APDE4APDE4B | |
| SCHEMBL1795319 | 0.70 | CA2 (0.55) | NAE1UBA3ATG7ADORA2BCA2 | |
| SCHEMBL23080273 | 0.70 | CA2 (0.55) | NAE1UBA3ATG7ADORA2BCA2 | |
| SCHEMBL23080288 | 0.70 | ATG7 (0.46) | NAE1UBA3ATG7CA2 | |
| SCHEMBL17889858 | 0.70 | AHCY (0.42) | NAE1UBA3ATG7ADORA2BCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070798-A1 | Inhibitors of E1 activating enzymes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070798-A1 | Inhibitors of E1 activating enzymes | ECE1, RNASE1, RCE1 | NAE1 41/4885UBA3 12/4885ADORA2A 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.