Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22986172 | 0.85 | EPHX1 (0.40) | NAAASMN1; SMN2HSD17B10EPHX1GAA | |
| SCHEMBL24177609 | 0.78 | SIGMAR1 (0.41) | NAAASMN1; SMN2EPHX1 | |
| SCHEMBL18056091 | 0.78 | ITGB3 (0.43) | — | |
| SCHEMBL18597007 | 0.76 | NAAA (0.38) | NAAASMN1; SMN2HSD17B10EPHX1ALDH1A1 | |
| SCHEMBL5909767 | 0.75 | CES2 (0.41) | NAAASMN1; SMN2EPHX1ALDH1A1GAA | |
| SCHEMBL18597013 | 0.73 | SMN1; SMN2 (0.41) | NAAASMN1; SMN2GAAHDAC8HDAC6 | |
| SCHEMBL14943216 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX1KDM4EALDH1A1GAA | |
| SCHEMBL24860034 | 0.72 | NAAA (0.40) | NAAASMN1; SMN2HSD17B10EPHX1 | |
| SCHEMBL10669991 | 0.71 | LMNA (0.43) | NAAASMN1; SMN2HSD17B10LMNAKMT2A | |
| SCHEMBL10669986 | 0.71 | LMNA (0.43) | NAAASMN1; SMN2HSD17B10LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046549-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2021-03-11 | — | — | WO | disclosed |