Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.43 |
| ▸ | CTSB | P07858 | 5/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSH | P09668 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24177609 | 0.84 | SIGMAR1 (0.41) | ITGB3ITGA2B | |
| SCHEMBL23085465 | 0.78 | NAAA (0.38) | — | |
| SCHEMBL24860034 | 0.77 | NAAA (0.40) | ITGB3ITGA2BCPB2 | |
| SCHEMBL20414838 | 0.77 | SLC6A5 (0.57) | — | |
| SCHEMBL21031588 | 0.77 | DPP7 (0.50) | ITGB3ITGA2B | |
| SCHEMBL15095584 | 0.77 | CPB2 (0.65) | CPB2 | |
| SCHEMBL13227701 | 0.76 | TPSAB1 (0.42) | CPB2CTSBCTSSCTSHCTSK | |
| SCHEMBL29866337 | 0.76 | GSR (0.44) | ITGB3ITGA2BCPB2 | |
| SCHEMBL22986172 | 0.74 | EPHX1 (0.40) | — | |
| SCHEMBL9716618 | 0.74 | CPB2 (0.55) | CPB2CTSBCTSSCTSHCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160251407-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2016-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160251407-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | GPR119, INSR, IRS1 | ITGB3 358/4885ITGA2B 329/4885CPB2 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.