SCHEMBL231203

SCHEMBL231203

[CH2]c1cccc(COC)c1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.41
AGXT P21549 2/20 0.41
FFAR1 O14842 1/20 0.39
ERN1 O75460 1/20 0.38
MAOB P27338 5/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
BRD4 O60885 1/20 0.36
CREBBP Q92793 1/20 0.36
MIF P14174 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2263098 0.84 IDO1 (0.37) IDO1AGXTMAOB
SCHEMBL487468 0.84 IDO1 (0.48) IDO1AGXTFFAR1ERN1MAOB
SCHEMBL896415 0.79 IDO1 (0.33) IDO1AGXTMAOB
SCHEMBL28044711 0.79 ENPP2 (0.41)
SCHEMBL2262212 0.79 TSHR (0.38) IDO1AGXT
SCHEMBL1004736 0.78 IDO1 (0.41) IDO1AGXTFFAR1ERN1MAOB
SCHEMBL15260899 0.78 CYP3A4 (0.37) IDO1AGXT
SCHEMBL1338691 0.77 AGXT (0.55) IDO1AGXTERN1L3MBTL1BRD4
SCHEMBL29644212 0.77 AGXT (0.55) IDO1AGXTERN1L3MBTL1BRD4
SCHEMBL3056959 0.76 CHRM2 (0.39) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11992012-B2 Diaminotriazine compounds BASF SE (DE) 2024-05-28 US disclosed
US-20210186021-A1 DIAMINOTRIAZINE COMPOUNDS BASF SE (DE) 2021-06-24 US disclosed
EP-2647644-B1 2'-O-MODIFIED RNA WAVE LIFE SCIENCES JAPAN INC (JP) 2020-09-09 EP disclosed
WO-2019025153-A1 USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-07 WO disclosed
US-10065926-B2 Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-09-04 US disclosed
US-20180199575-A1 SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-07-19 US disclosed
EP-3322296-A1 SUBSTITUTED OXO-TETRAHYDROQUINOLINYL-PHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS Bayer CropScience Aktiengesellschaft (DE) 2018-05-23 EP disclosed
US-20180020662-A1 Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-25 US disclosed
EP-3256448-A1 SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS Bayer CropScience Aktiengesellschaft (DE) 2017-12-20 EP disclosed
EP-3051946-B1 USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AG (DE) 2017-11-29 EP disclosed
CN-100582087-C 2-amino-bicyclo [3.1.0] hexane-2, 6-dicarboxylic acid ester derivatives TAISHO PHARMACEUTICAL CO LTD 2010-01-20 CN disclosed
US-20090306408-A1 2-Amino-Bicyclo (3.1.0) Hexane-2,6-Dicarboxylic Ester Derivative TAISHO PHARMACEUTICAL CO., LTD. (JP) 2009-12-10 US disclosed
EP-2123630-A1 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative Taisho Pharmaceutical Co. Ltd. (JP) 2009-11-25 EP disclosed
US-20080090914-A1 Staining Composition For Staining An Ophthalmic Membrane NATIONAL UNIVERSITY CORPORATION KYUSHU UNIVERSITY (JP) 2008-04-17 US disclosed
EP-1819366-A4 A STAINING COMPOSITION FOR STAINING AN OPHTHALMIC MEMBRANE UNIV KYUSHU NAT UNIV CORP (JP) 2008-04-16 EP disclosed
EP-1819366-A1 A STAINING COMPOSITION FOR STAINING AN OPHTHALMIC MEMBRANE Kyushu University, National University Corporation (JP) 2007-08-22 EP disclosed
US-20070021394-A1 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative TAISHO PHARMACEUTICAL CO., LTD. (JP) 2007-01-25 US disclosed
CN-1812960-A 2-amino-bicyclo [3.1.0] hexane-2, 6-dicarboxylic acid ester derivatives TAISHO PHARMACEUTICAL CO LTD (JP) 2006-08-02 CN disclosed
WO-2006062233-A1 A STAINING COMPOSITION FOR STAINING AN OPHTHALMIC MEMBRANE NATIONAL UNIVERSITY CORPORATION KYUSHU UNIVERSITY (JP) 2006-06-15 WO disclosed
EP-1637517-A1 2-AMINOBICYCLO 3.1.0 HEXANE-2,6-DICARBOXYLIC ESTER DERIVATIVE Taisho Pharmaceutical Co. Ltd. (JP) 2006-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10065926-B2 Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants SQOR, DHPS, QDPR IDO1 610/4885AGXT 123/4885FFAR1 3298/4885
US-20080090914-A1 Staining Composition For Staining An Ophthalmic Membrane BSG, CD68, MB IDO1 4058/4885AGXT 4677/4885FFAR1 2084/4885
US-20210186021-A1 DIAMINOTRIAZINE COMPOUNDS DDT, DAZAP1, DDC IDO1 113/4885AGXT 199/4885FFAR1 4593/4885
US-11992012-B2 Diaminotriazine compounds DDT, DAZAP1, DDC IDO1 113/4885AGXT 199/4885FFAR1 4593/4885
US-20090306408-A1 2-Amino-Bicyclo (3.1.0) Hexane-2,6-Dicarboxylic Ester Derivative GRIK4, GRIN2D, GRIN2C IDO1 2753/4885AGXT 1813/4885FFAR1 39/4885
US-20070021394-A1 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative GRIN2C, GRIK4, GRIN2B IDO1 3182/4885AGXT 1984/4885FFAR1 39/4885
US-20180020662-A1 Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants CBR3, CBR1, CBS IDO1 1077/4885AGXT 131/4885FFAR1 3429/4885
US-20180199575-A1 SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS PPA1, PHOSPHO1, PIP4K2C IDO1 1337/4885AGXT 86/4885FFAR1 2704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.