Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665945 | 0.91 | ALDH1A1 (0.58) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 | |
| SCHEMBL235829 | 0.85 | SMAD3 (0.40) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 | |
| SCHEMBL29461682 | 0.85 | SMAD3 (0.40) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 | |
| SCHEMBL37698 | 0.84 | HPGD (0.54) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 | |
| SCHEMBL5148271 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 | |
| SCHEMBL17515090 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 | |
| Cyanide SCHEMBL6533545 | 0.82 | SMAD3 (0.38) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 | |
| SCHEMBL134733 | 0.82 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 | |
| SCHEMBL30887310 | 0.82 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 | |
| SCHEMBL79627 | 0.82 | HPGD (0.63) | ALDH1A1HPGDBRCA1HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589475-A | Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein | 北京欧凯纳斯生化科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| US-9939447-B2 | Methods and compositions for analyzing proteins | MONOGRAM BIOSCIENCES, INC. (US) | 2018-04-10 | — | — | US | claimed |
| US-20160069893-A1 | Methods and Compositions for Analyzing Proteins | MONOGRAM BIOSCIENCES, INC. (US) | 2016-03-10 | — | — | US | claimed |
| US-9110075-B2 | Compositions for analyzing proteins | MONOGRAM BIOSCIENCES, INC. (US) | 2015-08-18 | — | — | US | claimed |
| US-20080311674-A1 | METHODS AND COMPOSITIONS FOR ANALYZING PROTEINS | MONOGRAM BIOSCIENCES, INC. (US) | 2008-12-18 | — | — | US | claimed |
| EP-1599492-A4 | RECEPTOR DEORPHANIZATION USING TAGGED MOLECULAR LIBRARIES | VIROLOGIC INC (US) | 2008-09-24 | — | — | EP | claimed |
| EP-1456657-A4 | TAGGED MICROPARTICLE COMPOSITIONS AND METHODS | ACLARA BIOSCIENCES INC (US) | 2008-03-12 | — | — | EP | claimed |
| EP-1581796-A4 | MULTIPLEX ANALYTICAL PLATFORM USING MOLECULAR TAGS | ACLARA BIOSCIENCES INC (US) | 2008-02-13 | — | — | EP | claimed |
| EP-1478765-A4 | MULTIPLEX ANALYSIS USING MEMBRANE-BOUND SENSITIZERS | ACLARA BIOSCIENCES INC (US) | 2006-12-06 | — | — | EP | claimed |
| US-20060127947-A1 | Receptor deorphanization using tagged molecular libraries | MONOGRAM BIOSCIENCES, INC. | 2006-06-15 | — | — | US | claimed |
| WO-2003042699-A1 | TAGGED MICROPARTICLE COMPOSITIONS AND METHODS | ACLARA BIOSCIENCES INC. (US) | 2003-05-22 | — | — | WO | claimed |
| US-20030013126-A1 | Methods and compositions for analyzing proteins | MONOGRAM BIOSCIENCES, INC. | 2003-01-16 | — | — | US | claimed |
| WO-2002095356-A2 | METHODS AND COMPOSITIONS FOR ANALYZING PROTEINS | ACLARA BIOSCIENCES, INC. (US) | 2002-11-28 | — | — | WO | claimed |
| US-20020081616-A1 | 4,7-dichlorofluorescein dyes as molecular probes | THE PERKIN-ELMER CORPORATION | 2002-06-27 | — | — | US | claimed |
| EP-0500779-B1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | PERKIN ELMER CORP (US) | 1999-04-21 | — | — | EP | claimed |
| JP-2523423-B2 | — | — | 1996-08-07 | — | — | JP | claimed |
| EP-0500779-A4 | — | — | 1994-02-23 | — | — | EP | claimed |
| US-5188934-A | Long wavelength, narrow emission bandwidth fluorescent dyes; automatic DNA sequencing | APPLIED BIOSYSTEMS, INC. (US) | 1993-02-23 | — | — | US | claimed |
| EP-0500779-A1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | THE PERKIN-ELMER CORPORATION (US) | 1992-09-02 | — | — | EP | claimed |
| WO-1991007507-A1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | APPLIED BIOSYSTEMS, INC. (US) | 1991-05-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020081616-A1 | 4,7-dichlorofluorescein dyes as molecular probes | SPAG5, SPG11, SPIN4 | ALDH1A1 658/4885HPGD 3902/4885BRCA1 3372/4885 |
| US-20160069893-A1 | Methods and Compositions for Analyzing Proteins | PTMS, ANPEP, NUDT21 | ALDH1A1 4389/4885HPGD 3744/4885BRCA1 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.