SCHEMBL23133168

SCHEMBL23133168

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)C(CCC(=O)O)NC(C)=O)C(=O)N[C@H](C=O)CC(=O)O

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TASP1 Q9H6P5 1/20 0.43
▸ BACE1 P56817 7/20 0.39
▸ GNPAT O15228 1/20 0.39
▸ BMP1 P13497 2/20 0.37
▸ CTSD P07339 4/20 0.36
▸ BACE2 Q9Y5Z0 1/20 0.36
▸ CASP1 P29466 1/20 0.34
▸ PTPN1 P18031 1/20 0.34
▸ SIRT5 Q9NXA8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1499722 1.00 TASP1 (0.43) TASP1BACE1GNPATBMP1CTSD
SCHEMBL23133286 1.00 TASP1 (0.43) TASP1BACE1GNPATBMP1CTSD
SCHEMBL29946126 0.88 TASP1 (0.45) TASP1BACE1GNPATBMP1CTSD
SCHEMBL20257262 0.87 FNTA (0.42) TASP1BMP1CASP1
SCHEMBL29664764 0.84 TASP1 (0.56) TASP1BACE1GNPATBMP1BACE2
SCHEMBL12149975 0.83 BACE1 (0.47) BACE1GNPATBMP1CTSDBACE2
SCHEMBL24616790 0.83 TASP1 (0.48) TASP1GNPATBMP1PTPN1SIRT5
SCHEMBL29946268 0.80 TASP1 (0.51) TASP1BACE1GNPATBMP1BACE2
SCHEMBL31107824 0.79 GNPAT (0.51) BACE1GNPATBACE2
SCHEMBL30464991 0.79 GNPAT (0.51) BACE1GNPATBACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210088504-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2021-03-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210088504-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF SENP8, SENP6, SENP7 TASP1 1024/4885BACE1 1145/4885GNPAT 2297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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