SCHEMBL20257262

SCHEMBL20257262

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)CCCC(=O)O)C(=O)N[C@H](C=O)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 4/20 0.42
▸ FNTB P49356 4/20 0.42
▸ PGGT1B P53609 1/20 0.40
▸ NMT2 O60551 1/20 0.38
▸ NMT1 P30419 1/20 0.38
▸ TASP1 Q9H6P5 1/20 0.36
▸ CASP1 P29466 2/20 0.36
▸ CYP2C9 P11712 1/20 0.35
▸ TLR2 O60603 1/20 0.34
▸ TACR3 P29371 1/20 0.34
▸ BMP1 P13497 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23133286 0.87 TASP1 (0.43) TASP1CASP1BMP1
SCHEMBL23133168 0.87 TASP1 (0.43) TASP1CASP1BMP1
SCHEMBL1499722 0.87 TASP1 (0.43) TASP1CASP1BMP1
SCHEMBL24072491 0.78 DEGS1 (0.35) FNTAFNTBPGGT1BNMT2NMT1
SCHEMBL29946126 0.77 TASP1 (0.45) TASP1CASP1BMP1
SCHEMBL22623308 0.72 NOD1 (0.42) CASP1BMP1
SCHEMBL24961510 0.71 FNTA (0.62) FNTAFNTBPGGT1B
SCHEMBL29664764 0.71 TASP1 (0.56) TASP1CASP1BMP1
SCHEMBL18133071 0.71 BMP1 (0.48) TASP1CASP1BMP1
SCHEMBL21387167 0.70 FOLH1 (0.36) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10976306-B2 Protein degradation inducing tag and usage thereof TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2021-04-13 — — US disclosed
US-20180164289-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2018-06-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10976306-B2 Protein degradation inducing tag and usage thereof SENP8, SENP6, SENP7 FNTA 892/4885FNTB 648/4885PGGT1B 1756/4885
US-20180164289-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF SENP8, SENP6, SENP7 FNTA 892/4885FNTB 648/4885PGGT1B 1756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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