Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 5/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11163306 | 0.79 | ALDH1A1 (0.49) | ABL1HIF1AALDH1A1L3MBTL1MAPT | |
| SCHEMBL212774 | 0.78 | ACHE (0.45) | ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2318868 | 0.78 | HIF1A (0.47) | ABL1HIF1AALDH1A1L3MBTL1MAPT | |
| SCHEMBL2360146 | 0.77 | TEK (0.49) | — | |
| SCHEMBL914198 | 0.76 | F2R (0.44) | ABL1HIF1AALDH1A1L3MBTL1MAPT | |
| SCHEMBL2327132 | 0.75 | WNT3A (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL21935795 | 0.74 | CYP2A6 (0.47) | ABL1HIF1AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL24932334 | 0.74 | MAPT (0.55) | ABL1HIF1AALDH1A1L3MBTL1MAPT | |
| SCHEMBL2321685 | 0.73 | KIF11 (0.41) | ABL1 | |
| SCHEMBL23406098 | 0.73 | KDM4E (0.60) | ABL1ALDH1A1L3MBTL1MAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |