SCHEMBL2321685

SCHEMBL2321685

Cc1ccc(-c2ccc(NC=O)nc2)cc1F

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.41
ERN1 O75460 1/20 0.40
ABL1 P00519 14/20 0.39
KMO O15229 2/20 0.39
CHRNA7 P36544 1/20 0.38
WNT3A P56704 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2324964 0.82 EPHB4 (0.48) KMO
SCHEMBL2327132 0.82 WNT3A (0.47) WNT3A
SCHEMBL2321676 0.79 KIF11 (0.41) KIF11ABL1KMOCHRNA7
SCHEMBL2360453 0.78 WNT3A (0.42) WNT3A
SCHEMBL2360146 0.78 TEK (0.49) WNT3A
SCHEMBL24072334 0.74 ABL1 (0.40) ABL1
SCHEMBL2318871 0.73 ABL1 (0.44) ABL1
SCHEMBL212774 0.73 ACHE (0.45) WNT3A
SCHEMBL2320835 0.72 FLT1 (0.44)
SCHEMBL2320060 0.71 DEGS1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011094890-A1 PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS ARGUSINA INC. (US) 2011-08-11 WO disclosed