SCHEMBL2360146

SCHEMBL2360146

O=CNc1ccc(-c2ccc(F)cc2)cn1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TEK Q02763 2/20 0.49
KDR P35968 1/20 0.49
GPR55 Q9Y2T6 12/20 0.42
WNT3A P56704 1/20 0.40
DGAT1 O75907 1/20 0.38
FYN P06241 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212099 0.85 FFAR2 (0.40)
SCHEMBL212774 0.84 ACHE (0.45) WNT3A
SCHEMBL2327132 0.83 WNT3A (0.47) TEKGPR55WNT3A
SCHEMBL2320060 0.82 DEGS1 (0.45) TEKKDR
SCHEMBL2360453 0.82 WNT3A (0.42) TEKWNT3A
SCHEMBL2359971 0.81 KIF11 (0.43) TEKKDR
SCHEMBL2321384 0.78 DEGS1 (0.41) TEKKDRGPR55
SCHEMBL2325030 0.78 DEGS1 (0.48) WNT3AFYN
SCHEMBL2324455 0.78 TEK (0.55) TEK
SCHEMBL2321685 0.78 KIF11 (0.41) WNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011094890-A1 PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS ARGUSINA INC. (US) 2011-08-11 WO disclosed