Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360146 | 0.84 | TEK (0.49) | WNT3A | |
| SCHEMBL2320060 | 0.84 | DEGS1 (0.45) | DEGS1ALDH1A1NPC1NFKB1RAB9A | |
| SCHEMBL2360453 | 0.84 | WNT3A (0.42) | WNT3AALDH1A1NPC1NFKB1RAB9A | |
| SCHEMBL2327132 | 0.82 | WNT3A (0.47) | WNT3AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21935795 | 0.81 | CYP2A6 (0.47) | WNT3ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2320835 | 0.80 | FLT1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2359971 | 0.80 | KIF11 (0.43) | DEGS1NPC1RAB9A | |
| SCHEMBL2321384 | 0.80 | DEGS1 (0.41) | DEGS1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2325030 | 0.80 | DEGS1 (0.48) | DEGS1WNT3AALDH1A1NPC1RAB9A | |
| SCHEMBL2318871 | 0.78 | ABL1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |