Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | HTR1D | P28221 | 4/20 | 0.43 |
| ▸ | HTR1B | P28222 | 4/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31501222 | 0.81 | L3MBTL1 (0.57) | HTR1AHTR1DHTR1BCHRNA3ALDH1A1 | |
| SCHEMBL31198254 | 0.78 | CHRM3 (0.48) | CHRNA3ALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL25212045 | 0.78 | CHRNA3 (0.43) | DRD2HTR1ACHRNA3ALDH1A1L3MBTL1 | |
| SCHEMBL378787 | 0.74 | ALDH1A1 (0.51) | ALDH1A1MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL28010902 | 0.74 | TDP1 (0.47) | ALDH1A1MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL15882797 | 0.74 | PDGFRB (0.55) | ALDH1A1MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL31634147 | 0.72 | SIRT5 (0.47) | ALDH1A1MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL23199839 | 0.72 | SMN1; SMN2 (0.52) | HTR1AHTR1DHTR1BALDH1A1MEN1 | |
| SCHEMBL31482564 | 0.72 | TDP1 (0.44) | ALDH1A1MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL34462112 | 0.72 | TDP1 (0.44) | ALDH1A1MEN1CYP1A2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801553-A2 | PRODRUGS OF FULVESTRANT | Kashiv Biosciences, LLC (US) | 2021-04-14 | — | — | EP | disclosed |