Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 5/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320565 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CES1MAOAKMT2AMEN1 | |
| SCHEMBL3039377 | 0.76 | MAOA (0.45) | ALDH1A1CES1MAOAMAPTBCHE | |
| SCHEMBL30191469 | 0.72 | NOTUM (0.39) | ALDH1A1CES1MAOANPC1RAB9A | |
| SCHEMBL15573886 | 0.72 | NOTUM (0.39) | ALDH1A1CES1MAOANPC1RAB9A | |
| SCHEMBL8003247 | 0.72 | CES1 (0.41) | ALDH1A1CES1MAOAKMT2AMEN1 | |
| SCHEMBL10440547 | 0.72 | ALDH1A1 (0.42) | ALDH1A1CES1MAOAKMT2AMEN1 | |
| SCHEMBL8154115 | 0.69 | MAPT (0.43) | ALDH1A1CES1MAOAKMT2AMEN1 | |
| SCHEMBL11813906 | 0.68 | HTR6 (0.37) | ALDH1A1CES1MAOABCHECYP1A2 | |
| SCHEMBL335207 | 0.68 | SRD5A2 (0.43) | ALDH1A1CES1MAOAKDM4ESMN1; SMN2 | |
| SCHEMBL31147237 | 0.68 | SRD5A2 (0.43) | ALDH1A1CES1MAOAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184800-B1 | OXYGEN PERMEABLE SOFT CONTACT LENS MATERIAL | Toyo Contact Lens Co., Ltd. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4649184-A | UNSATURATED POLYSILOXANE COPOLYMER WITH MONOMER HAVING SIYLATED HYDROXYL GROUPS | TOYO CONTACT LENS CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0184800-A2 | Oxygen permeable soft contact lens material | Toyo Contact Lens Co., Ltd. (JP) | 1986-06-18 | — | — | EP | disclosed |