SCHEMBL23243998

SCHEMBL23243998

CC(=O)N[C@H]1[C@H](OCCOCC=O)O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.58
▸ MAPT P10636 1/20 0.58
▸ CYP2C9 P11712 1/20 0.58
▸ CYP2C19 P33261 1/20 0.58
▸ LMNA P02545 3/20 0.57
▸ POLB P06746 2/20 0.57
▸ ALDH1A1 P00352 2/20 0.57
▸ KMT2A Q03164 1/20 0.53
▸ KDM4E B2RXH2 1/20 0.46
▸ CYP2D6 P10635 1/20 0.44
▸ THRB P10828 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ CA2 P00918 7/20 0.40
▸ CA1 P00915 6/20 0.40
▸ CA9 Q16790 6/20 0.40
▸ CA12 O43570 5/20 0.40
▸ TGM2 P21980 1/20 0.40
▸ MMP12 P39900 1/20 0.39
▸ TSHR P16473 1/20 0.38
▸ NR3C1 P04150 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23243932 0.99 CYP3A4 (0.58) CYP3A4MAPTCYP2C9CYP2C19LMNA
SCHEMBL23069413 0.99 CYP3A4 (0.58) CYP3A4MAPTCYP2C9CYP2C19LMNA
SCHEMBL25747109 0.99 CYP3A4 (0.58) CYP3A4MAPTCYP2C9CYP2C19LMNA
SCHEMBL23243960 0.99 CYP3A4 (0.58) CYP3A4MAPTCYP2C9CYP2C19LMNA
SCHEMBL23069384 0.90 LMNA (0.62) CYP3A4MAPTCYP2C9CYP2C19LMNA
SCHEMBL23243934 0.90 CYP3A4 (0.50) CYP3A4MAPTCYP2C9CYP2C19LMNA
SCHEMBL24531300 0.89 CYP3A4 (0.62) CYP3A4MAPTCYP2C9CYP2C19LMNA
SCHEMBL23618355 0.89 CYP3A4 (0.62) CYP3A4MAPTCYP2C9CYP2C19LMNA
SCHEMBL24239926 0.89 CYP3A4 (0.62) CYP3A4MAPTCYP2C9CYP2C19LMNA
SCHEMBL24531302 0.89 CYP3A4 (0.62) CYP3A4MAPTCYP2C9CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2026-04-16 — — US disclosed
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2024-11-14 — — US disclosed
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same SANOFI (FR) 2024-02-13 — — US disclosed
US-20220372063-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2022-11-24 — — US disclosed
EP-4025582-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2022-07-13 — — EP disclosed
US-20210115075-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI (FR) 2021-04-22 — — US disclosed
CN-112105625-A Nucleotide precursors, nucleotide analogs, and oligomeric compounds containing the same 赛诺菲 2020-12-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same RNMT, RRM2B, RRM2 CYP3A4 4825/4885MAPT 4775/4885CYP2C9 4734/4885
US-20210115075-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME RNMT, RRM2B, RRM2 CYP3A4 4825/4885MAPT 4775/4885CYP2C9 4734/4885
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME NSUN2, NSUN3, SNRPA CYP3A4 4436/4885MAPT 4866/4885CYP2C9 4557/4885
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME RNMT, NSUN2, ADAR CYP3A4 4855/4885MAPT 4602/4885CYP2C9 4869/4885
US-20220372063-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS DCLRE1B, UPF1, IGF2BP1 CYP3A4 4877/4885MAPT 4631/4885CYP2C9 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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