Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2326938 | 0.92 | LDHA (0.39) | IKBKBADORA2ALDHAIRAK4PTGER1 | |
| SCHEMBL2334798 | 0.89 | PTGER1 (0.39) | IKBKBADORA2ALDHAKDM4EHSD17B10 | |
| SCHEMBL2328798 | 0.89 | PTGER1 (0.38) | IKBKBADORA2ALDHAALDH1A1KDM4E | |
| SCHEMBL2329257 | 0.89 | IKBKB (0.43) | IKBKBADORA2AKMT2ARXRARXRB | |
| SCHEMBL1704018 | 0.88 | IKBKB (0.43) | IKBKBADORA2AKMT2ARXRARXRB | |
| SCHEMBL2327504 | 0.87 | PTGER1 (0.38) | IKBKBADORA2APTGER1CSNK2A1SMN1; SMN2 | |
| SCHEMBL2324316 | 0.85 | IKBKB (0.47) | IKBKBADORA2AKMT2ARXRARXRB | |
| SCHEMBL2327049 | 0.84 | IKBKB (0.48) | IKBKBADORA2AKMT2ARXRARXRB | |
| SCHEMBL2332145 | 0.83 | MMP1 (0.38) | IKBKBLDHAALDH1A1HPGDKDM4E | |
| SCHEMBL1704159 | 0.79 | IKBKB (0.44) | IKBKBADORA2AKMT2ARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | claimed |