Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 6/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2332145 | 0.92 | MMP1 (0.38) | PTGER1IKBKBKDM4EMMP1MMP2 | |
| SCHEMBL2328798 | 0.91 | PTGER1 (0.38) | PTGER1IKBKBKDM4EMMP1MMP2 | |
| SCHEMBL2329257 | 0.91 | IKBKB (0.43) | PTGER1IKBKBFPR2LDHAADORA2A | |
| SCHEMBL2324749 | 0.89 | IKBKB (0.46) | PTGER1IKBKBKDM4EHSD17B10FPR2 | |
| SCHEMBL2327504 | 0.89 | PTGER1 (0.38) | PTGER1IKBKBADORA2A | |
| SCHEMBL2326938 | 0.87 | LDHA (0.39) | PTGER1IKBKBFPR2LDHAADORA2A | |
| SCHEMBL1703980 | 0.85 | PTGER1 (0.35) | PTGER1IKBKBKDM4EPPARGNCOA2 | |
| SCHEMBL2327721 | 0.85 | FPR2 (0.47) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL2327745 | 0.84 | IKBKB (0.39) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL2324724 | 0.84 | IKBKB (0.37) | IKBKBKDM4EPPARGNCOA2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | claimed |
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | disclosed |