Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 5/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 5/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19645417 | 0.87 | GNAI3 (0.49) | GNAI3GNAI1GNAO1NPC1CACNA1B | |
| SCHEMBL21871200 | 0.85 | HSD11B1 (0.48) | GNAI3GNAI1GNAO1NPC1CACNA1B | |
| SCHEMBL24943358 | 0.85 | HRH3 (0.39) | GNAI3GNAI1GNAO1NPC1CACNA1B | |
| SCHEMBL23511722 | 0.84 | GNAI3 (0.48) | GNAI3GNAI1GNAO1NPC1 | |
| SCHEMBL22605257 | 0.82 | NPC1 (0.39) | GNAI3GNAI1GNAO1NPC1CACNA1B | |
| SCHEMBL1109055 | 0.82 | CPN1 (0.40) | CPN1CPB2KMT2ADPP4DPP8 | |
| SCHEMBL19738849 | 0.82 | ALDH1A1 (0.50) | GNAI3GNAI1GNAO1NPC1 | |
| SCHEMBL19184868 | 0.82 | ITGB3 (0.37) | GNAI3GNAI1GNAO1NPC1CACNA1B | |
| SCHEMBL22874723 | 0.81 | NPC1 (0.46) | GNAI3GNAI1GNAO1NPC1CACNA1B | |
| SCHEMBL22874752 | 0.80 | NPC1 (0.44) | GNAI3GNAI1GNAO1NPC1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210113534-A1 | COMPOUNDS | THE UNIVERSITY OF SHEFFIELD (GB) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113534-A1 | COMPOUNDS | MRGPRX2, MC2R, ADM2 | GNAI3 772/4885GNAI1 1029/4885GNAO1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.