Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415976 | 0.82 | — | — | |
| Methane SCHEMBL322257 | 0.76 | — | — | |
| Naphthalene SCHEMBL11604909 | 0.71 | CYP2A6 (0.57) | HTR6TSHRALDH1A1HSD17B10TDP1 | |
| Ethane SCHEMBL2433111 | 0.71 | — | — | |
| Benzene SCHEMBL249062 | 0.67 | CA5A (0.67) | HTR6TSHRTP53ALDH1A1TDP1 | |
| Benzene SCHEMBL107628 | 0.67 | ALDH1A1 (0.47) | HTR6TSHRTP53ALDH1A1HSD17B10 | |
| Benzene SCHEMBL1470009 | 0.67 | TSHR (0.42) | HTR6TSHRTP53ALDH1A1HSD17B10 | |
| Benzene SCHEMBL10457003 | 0.67 | CA1 (0.67) | HTR6TSHRTP53CA12CA1 | |
| Benzene SCHEMBL6258462 | 0.67 | CA1 (0.67) | HTR6TSHRTP53CA12CA1 | |
| SCHEMBL9722581 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115044237-A | Coating composition, preparation method thereof and coating | 苏州北辰新材料科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-115044237-A | Coating composition, preparation method thereof and coating | 苏州北辰新材料科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-103833723-B | The manufacture method of cyclic sulfonic acid ester and intermediate thereof | 和光纯药工业株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-103833723-A | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | WAKO PURE CHEM IND LTD | 2014-06-04 | — | — | CN | disclosed |
| CN-102471305-B | Process for producing cyclic sulfonic acid ester and intermediate thereof | WAKO PURE CHEM IND LTD | 2014-01-29 | — | — | CN | disclosed |
| CN-102471305-A | Process for producing cyclic sulfonic acid ester and intermediate thereof | WAKO PURE CHEM IND LTD | 2012-05-23 | — | — | CN | disclosed |
| EP-1666483-B1 | PROCESS FOR PRODUCING 3-CHLOROMETHYL-3-CEPHEM DERIVATIVE | NIPPON CHEMICAL IND COMPANY LTD (JP) | 2011-08-17 | — | — | EP | disclosed |
| US-7507812-B2 | Process for producing 3-chloromethyl-3-cephem derivatives | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2009-03-24 | — | — | US | disclosed |
| US-20070027313-A1 | Reacting a 6-(1-aryloxycarbonyl-2-methallyl)thiazolineazetidinone with an arylsulfonyl halide to cleave the thiazole ring, chlorinating the methallyl group, and cyclizing the product with an alkali metat alcoholate in an ether to produce crystals of the cephem derivative | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
| EP-1666483-A1 | PROCESS FOR PRODUCING 3-CHLOROMETHYL-3-CEPHEM DERIVATIVE | NIPPON CHEMICAL INDUSTRIAL COMPANY LIMITED (JP) | 2006-06-07 | — | — | EP | disclosed |
| CN-1537097-A | Method for producing acid anhydride | ��ʽ�����ɽ | 2004-10-13 | — | — | CN | disclosed |
| CN-1125027-C | Process for producing di-tert-butyl dicarbonate | TOKUYAMA CORP (JP) | 2003-10-22 | — | — | CN | disclosed |
| CN-1222504-A | Process for producing di-tert-butyl dicarbonate | TOKUYAMA CORP (JP) | 1999-07-14 | — | — | CN | disclosed |
| EP-0114729-B1 | PROCESS FOR PREPARING AZETIDINONE DERIVATIVES | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4566996-A | Process for preparing azetidinone derivatives | Otsuke Kagaku Yakuhin Kabushiki Kaisha (JP) | 1986-01-28 | — | — | US | disclosed |
| EP-0114729-A1 | Process for preparing azetidinone derivatives | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1984-08-01 | — | — | EP | disclosed |
| US-4128586-A | Catalytic reduction of aromatic sulfonyl halides with hydrogen sulfide to yield aromatic thiols | ALLIED CHEMICAL CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |
| US-4089865-A | Certain thiazole compounds | SYNTEX (U.S.A.) INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4001421-A | THIAZOLE CARDIOVASCULAR AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3982010-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027313-A1 | Reacting a 6-(1-aryloxycarbonyl-2-methallyl)thiazolineazetidinone with an arylsulfonyl halide to cleave the thiazole ring, chlorinating the methallyl group, and cyclizing the product with an alkali metat alcoholate in an ether to produce crystals of the cephem derivative | ADH5, ADH1A, ACR | HTR6 1781/4885TSHR 1950/4885TP53 2092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.