SCHEMBL23298

SCHEMBL23298

CCOc1ccc(OBOc2ccc(OCC)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.70
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
LTA4H P09960 2/20 0.52
ALDH1A1 P00352 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 2/20 0.47
PARP10 Q53GL7 1/20 0.47
RELA Q04206 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
ADRA2A P08913 2/20 0.45
MAPT P10636 1/20 0.45
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14634377 0.93 NQO1 (0.61) NQO1TSHRTDP1LTA4HALDH1A1
SCHEMBL3095609 0.91 LTA4H (0.67) NQO1TSHRTDP1LTA4HALDH1A1
1,4-Diethoxybenzene SCHEMBL124015 0.84 NQO1 (1.00) NQO1TSHRTDP1LTA4HALDH1A1
1,4-Diethoxybenzene SCHEMBL28186701 0.84 NQO1 (1.00) NQO1TSHRTDP1LTA4HALDH1A1
SCHEMBL4834852 0.82 NQO1 (0.52) NQO1TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL14664976 0.81 NQO1 (0.64) NQO1TSHRTDP1LTA4HALDH1A1
SCHEMBL3707799 0.81 LTA4H (0.53) NQO1LTA4HALDH1A1SMN1; SMN2CA12
SCHEMBL1018667 0.81 LTA4H (0.55) TSHRLTA4HSMN1; SMN2CA12CA1
1,4-Diethoxybenzene SCHEMBL11794798 0.81 NQO1 (0.93) NQO1TSHRTDP1LTA4HALDH1A1
1,4-Diethoxybenzene SCHEMBL27616183 0.78 NQO1 (0.88) NQO1TSHRTDP1LTA4HALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102327-A1 METHODS FOR COVALENTLY FUNCTIONALIZING SEMICONDUCTING SINGLE WALLED CARBON NANOTUBES AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2026-05-15 WO disclosed
CN-120077035-A As CX32,4, 6-Trisubstituted 1,3, 5-triazines as modulators of CR1 阿斯利康(瑞典)有限公司 2025-05-30 CN disclosed
CN-113748184-B Boron-containing cyclic light-emitting compound and color conversion film containing same 日东电工株式会社 2025-04-04 CN disclosed
US-12227496-B2 Substituted bicyclic compounds as farnesoid X receptor modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2025-02-18 US disclosed
CN-112384515-B Imidazopyrimidines and triazolopyrimidines as A2A/A2B inhibitors 因赛特公司 2024-12-10 CN disclosed
EP-4448513-A1 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF BeiGene Switzerland GmbH (CH) 2024-10-23 EP disclosed
CN-118702683-A Phenyl ethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods thereof 凌科药业(杭州)有限公司 2024-09-27 CN disclosed
CN-113164459-B Monoacylglycerol lipase modulators 詹森药业有限公司 2024-09-03 CN disclosed
CN-118401514-A 3, 4-Dihydroisoquinolin-1 (2H) -one derivatives as STING antagonists and uses thereof 百济神州有限公司 2024-07-26 CN disclosed
CN-118076348-A N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same 欧罗法玛实验室股份公司 2024-05-24 CN disclosed
US-20040152704-A1 Bicyclic-substituted amines as histamine-3 receptor ligands ABBVIE INC. 2004-08-05 US disclosed
EP-1425015-A2 TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-06-09 EP disclosed
WO-2004043458-A1 BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2004-05-27 WO disclosed
US-20040019045-A1 2-(4-(4-(4-Fluorophenyl)-3,5-imethyl-1H-pyrazol-1-yl)phenyl) ethyl (4-methylphenyl)sulfonylcarbamate ammonium salt, e.g., as an antagonist for Prostoglandin E receptor; analgesics; antipyretics; antiinflammatory agents HIRANO MISATO (JP) 2004-01-29 US disclosed
US-20030225110-A1 Tetrahydroquinoline derivatives as antithrombotic agents BRISTOL-MYERS SQUIBB PHARMA COMPANY 2003-12-04 US disclosed
WO-2003087061-A1 PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS PFIZER JAPAN INC. (JP) 2003-10-23 WO disclosed
US-20030144246-A1 Chromenylmethyl pyrimidinediamines as antibacterial agents BASILEA PHARMACEUTICA AG A SWISS COMPANY (CH) 2003-07-31 US disclosed
WO-2003015715-A2 TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-02-27 WO disclosed
EP-1278742-A1 CHROMENYLMETHYLPYRIMIDINEDIAMINES AS ANTIBACTERIAL AGENTS Basilea Pharmaceutica AG (CH) 2003-01-29 EP disclosed
WO-2001083476-A1 CHROMENYLMETHYL PYRIMIDINEDIAMINES AS ANTIBACTERIAL AGENTS BASILEA PHARMACEUTICA AG (CH) 2001-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225110-A1 Tetrahydroquinoline derivatives as antithrombotic agents TFPI, TFPI2, SERPINC1 NQO1 714/4885TSHR 2853/4885TDP1 1311/4885
US-12227496-B2 Substituted bicyclic compounds as farnesoid X receptor modulators FXR1, NR1H4, FXR2 NQO1 2251/4885TSHR 567/4885TDP1 4134/4885
US-20040019045-A1 2-(4-(4-(4-Fluorophenyl)-3,5-imethyl-1H-pyrazol-1-yl)phenyl) ethyl (4-methylphenyl)sulfonylcarbamate ammonium salt, e.g., as an antagonist for Prostoglandin E receptor; analgesics; antipyretics; antiinflammatory agents PTGER1, PTGS1, PTGIR NQO1 4195/4885TSHR 1639/4885TDP1 4607/4885
US-20030144246-A1 Chromenylmethyl pyrimidinediamines as antibacterial agents TK1, TPMT, CTSL NQO1 2249/4885TSHR 1219/4885TDP1 2623/4885
US-20040152704-A1 Bicyclic-substituted amines as histamine-3 receptor ligands HRH3, HRH4, HRH1 NQO1 2208/4885TSHR 361/4885TDP1 4305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.