Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341403 | 1.00 | TSHR (0.78) | TSHRTP53CYP2D6RECQLLMNA | |
| SCHEMBL23266974 | 1.00 | TSHR (0.78) | TSHRTP53CYP2D6RECQLLMNA | |
| SCHEMBL2596611 | 1.00 | TSHR (0.78) | TSHRTP53CYP2D6RECQLLMNA | |
| Water SCHEMBL10705613 | 0.98 | TSHR (0.75) | TSHRTP53CYP2D6RECQLLMNA | |
| Cadaverine Tartrate SCHEMBL16541102 | 0.92 | TSHR (0.85) | TSHRTP53CYP2D6RECQLLMNA | |
| SCHEMBL4190179 | 0.92 | TSHR (0.71) | TSHRTP53CYP2D6RECQLLMNA | |
| SCHEMBL3709855 | 0.92 | TSHR (0.71) | TSHRTP53CYP2D6RECQLLMNA | |
| SCHEMBL670257 | 0.88 | TSHR (1.00) | TSHRTP53CYP2D6RECQLLMNA | |
| SCHEMBL11886503 | 0.88 | TSHR (1.00) | TSHRTP53CYP2D6RECQLLMNA | |
| SCHEMBL223030 | 0.88 | TSHR (1.00) | TSHRTP53CYP2D6RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012131710-A2 | NOVEL PROCESS FOR THE SYNTHESIS OF INDOLINE DERIVATIVES | PANACEA BIOTEC LTD (IN) | 2012-10-04 | — | — | WO | claimed |
| WO-2011158257-A1 | PREPARATION PROCESS OF FESOTERODINE AND INTERMEDIATES | PANACEA BIOTEC LTD (IN) | 2011-12-22 | — | — | WO | claimed |
| EP-0141408-B1 | PROCESS FOR THE PREPARATION OF L(-)CARNITINE HYDROCHLORIDE AND OF L(-)CARNITINE INNER SALT | ISOM S.p.A. (IT) | 1989-08-23 | — | — | EP | claimed |
| US-11401266-B2 | Process for the preparation of an orexin receptor antagonist | Merck Sharp & Dohme (UK) Ltd. (GB) | 2022-08-02 | — | — | US | disclosed |
| US-20210309650-A1 | Process for the Prepartion of an Orexin Receptor Antagonist | MERCK SHARP & DOHME CORP. (US) | 2021-10-07 | — | — | US | disclosed |
| US-20210163474-A1 | METHOD FOR THE PREPARATION OF (4S)-4-(4-CYANO-2-METHOXYPHENYL)-5-ETHOXY-2,8-DIMETHYL-1,4-DIHYDRO-1-6-NAPHTHYRIDINE-3-CARBOX-AMIDE BY RACEMATE SEPARATION BY MEANS OF DIASTEREOMERIC TARTARIC ACID ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-03 | — | — | US | disclosed |
| US-10774069-B2 | Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making | PHARMAKEA, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| EP-3339300-B1 | METHOD FOR PREPARING THIENYL ALANINE HAVING OPTICAL ACTIVITY | AMINOLOGICS CO LTD (KR) | 2020-08-12 | — | — | EP | disclosed |
| US-10562879-B2 | Method for preparing thienyl alanine having optical activity | AMINOLOGICS CO., LTD. (KR) | 2020-02-18 | — | — | US | disclosed |
| US-20190202805-A1 | CRYSTALLINE FORMS OF A LYSYL OXIDASE-LIKE 2 INHIBITOR AND METHODS OF MAKING | PHARMAKEA, INC. | 2019-07-04 | — | — | US | disclosed |
| US-20180290996-A1 | METHOD FOR PREPARING THIENYL ALANINE HAVING OPTICAL ACTIVITY | AMINOLOGICS CO., LTD. (KR) | 2018-10-11 | — | — | US | disclosed |
| CN-1543385-A | Solder composition | ��ʿͨ��ʽ���� | 2004-11-03 | — | — | CN | disclosed |
| EP-1402990-A1 | SOLDER COMPOSITION | FUJI ELECTRIC CO., LTD. (JP) | 2004-03-31 | — | — | EP | disclosed |
| EP-0763010-A4 | ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL | SEPRACOR INC (US) | 1997-07-16 | — | — | EP | disclosed |
| US-5631264-A | NEUROLOGICAL DISORDERS | SANOFI WINTHROP, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0763010-A1 | ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL | SEPRACOR, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5554620-A | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof | STERLING WINTHROP INC. (US) | 1996-09-10 | — | — | US | disclosed |
| WO-1995032178-A1 | ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL | SEPRACOR, INC. (US) | 1995-11-30 | — | — | WO | disclosed |
| EP-0656359-A1 | Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts and compositionsand methods of use thereof | STERLING WINTHROP INC. (US) | 1995-06-07 | — | — | EP | disclosed |
| US-3932429-A | Novel azabicyclo octane derivative and process for preparing same | TANABE SEIYAKU CO., LTD (JA) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309650-A1 | Process for the Prepartion of an Orexin Receptor Antagonist | HCRTR2, HCRTR1, CRHR1 | TSHR 176/4885TP53 4877/4885CYP2D6 1439/4885 |
| US-10562879-B2 | Method for preparing thienyl alanine having optical activity | ALAD, AADAT, THOP1 | TSHR 1038/4885TP53 4082/4885CYP2D6 1174/4885 |
| US-11401266-B2 | Process for the preparation of an orexin receptor antagonist | HCRTR2, HCRTR1, CRHR1 | TSHR 160/4885TP53 4880/4885CYP2D6 1062/4885 |
| US-10774069-B2 | Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making | LOXL2, LOXL1, LOX | TSHR 4057/4885TP53 4717/4885CYP2D6 125/4885 |
| US-20180290996-A1 | METHOD FOR PREPARING THIENYL ALANINE HAVING OPTICAL ACTIVITY | ALAD, AADAT, THOP1 | TSHR 1038/4885TP53 4082/4885CYP2D6 1174/4885 |
| US-20210163474-A1 | METHOD FOR THE PREPARATION OF (4S)-4-(4-CYANO-2-METHOXYPHENYL)-5-ETHOXY-2,8-DIMETHYL-1,4-DIHYDRO-1-6-NAPHTHYRIDINE-3-CARBOX-AMIDE BY RACEMATE SEPARATION BY MEANS OF DIASTEREOMERIC TARTARIC ACID ESTERS | SRD5A1, NR4A1, SRD5A2 | TSHR 1011/4885TP53 3176/4885CYP2D6 13/4885 |
| US-20190202805-A1 | CRYSTALLINE FORMS OF A LYSYL OXIDASE-LIKE 2 INHIBITOR AND METHODS OF MAKING | LOXL2, LOXL1, LOX | TSHR 4057/4885TP53 4717/4885CYP2D6 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.