Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581000 | 0.81 | ALDH1A1 (0.43) | CRBNL3MBTL1PKMDUTALDH1A1 | |
| SCHEMBL41240 | 0.81 | PKM (0.42) | CRBNL3MBTL1PKMDUT | |
| SCHEMBL11546247 | 0.79 | DUT (0.41) | CRBNPKMDUT | |
| SCHEMBL5792152 | 0.79 | CRBN (0.42) | CRBNL3MBTL1PKMDUTALDH1A1 | |
| SCHEMBL6425133 | 0.77 | L3MBTL1 (0.43) | CRBNL3MBTL1PKMDUTALDH1A1 | |
| SCHEMBL16671885 | 0.77 | HTT (0.41) | CRBNPKMDUT | |
| SCHEMBL11580831 | 0.76 | GPR84 (0.41) | DUT | |
| SCHEMBL11583672 | 0.75 | PKM (0.44) | CRBNL3MBTL1PKMDUTALDH1A1 | |
| SCHEMBL9426408 | 0.73 | ALDH1A1 (0.40) | PKMDUTALDH1A1 | |
| SCHEMBL1673256 | 0.73 | KMT2A (0.42) | L3MBTL1PKMDUTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087408-A1 | OTIC FORMULATIONS FOR DRUG-INDUCED OTOTOXICITY | OTONOMY, INC. (US) | 2021-05-06 | — | — | WO | disclosed |