Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.40 |
| ▸ | CPS1 | P31327 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21465775 | 0.83 | HTT (0.43) | MTNR1BKDM4EALDH1A1LMNATSHR | |
| SCHEMBL23326618 | 0.80 | CHRNB2 (0.39) | — | |
| SCHEMBL30888638 | 0.73 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL26788238 | 0.70 | PTGDR2 (0.51) | PTGDR2KDM4EALDH1A1LMNA | |
| SCHEMBL12047054 | 0.70 | SMN1; SMN2 (0.53) | PTGDR2KDM4EALDH1A1LMNAGAA | |
| SCHEMBL23326213 | 0.69 | PTGDR2 (0.57) | PTGDR2MTNR1BMTNR1APROKR1KDM4E | |
| SCHEMBL30040477 | 0.69 | ALDH1A1 (0.46) | MTNR1BALDH1A1 | |
| SCHEMBL30039889 | 0.69 | ALDH1A1 (0.46) | MTNR1BALDH1A1 | |
| SCHEMBL1148370 | 0.68 | NPC1 (0.56) | PTGDR2MTNR1BMTNR1ACPS1KDM4E | |
| SCHEMBL1803184 | 0.68 | SIGMAR1 (0.39) | PTGDR2MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | GOSSAMER BIO SERVICES INC (US) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ULK1, PHKG2, PHKG1 | PTGDR2 1833/4885MTNR1B 1895/4885MTNR1A 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.