Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334833 | 0.79 | EPHX2 (0.43) | EPHX2ADRA2BRIPK1CES2CES1 | |
| SCHEMBL30060124 | 0.74 | PGR (0.31) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL15648368 | 0.72 | RIPK1 (0.35) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL30061036 | 0.72 | HTT (0.40) | HTR2AALDH1A1LMNASMN1; SMN2 | |
| Propionic Acid SCHEMBL29009760 | 0.71 | CES2 (0.50) | EPHX2RIPK1CES2CES1POLB | |
| SCHEMBL8622658 | 0.71 | EPHX2 (0.36) | EPHX2RIPK1CES2CES1ALPL | |
| SCHEMBL2176406 | 0.71 | HCAR3 (0.47) | NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3343171 | 0.69 | ALDH1A1 (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL3343176 | 0.69 | ALDH1A1 (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL8940097 | 0.68 | ALDH1A1 (0.48) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360160-A1 | Intermediates and their use for producing benzoxazine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-08-24 | — | — | EP | disclosed |