Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537232 | 0.88 | TSHR (0.33) | EPHX2TSHRALDH1A1GLARIPK1 | |
| SCHEMBL1345003 | 0.75 | ALDH1A1 (0.36) | TSHRALDH1A1GLARIPK1CES2 | |
| SCHEMBL9128725 | 0.73 | MAPT (0.32) | EPHX2TSHRALDH1A1LMNA | |
| SCHEMBL2487489 | 0.72 | TSHR (0.36) | TSHRALDH1A1GLA | |
| SCHEMBL17769749 | 0.72 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2334592 | 0.71 | EPHX2 (0.38) | EPHX2ALDH1A1RIPK1CES2CES1 | |
| SCHEMBL14845241 | 0.71 | CES2 (0.50) | RIPK1CES2CES1ALPLALPI | |
| Propionic Acid SCHEMBL29009760 | 0.70 | CES2 (0.50) | EPHX2TSHRALDH1A1RIPK1CES2 | |
| SCHEMBL8621652 | 0.70 | EPHX2 (0.35) | EPHX2ALDH1A1RIPK1CES2CES1 | |
| SCHEMBL20550632 | 0.68 | TSHR (0.42) | TSHRALDH1A1GLARIPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684942-B1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORP (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5430152-A | Heating aminoarylester in presence of chlorosulfonic acid, oleum | HOECHST CELANESE CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |