Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24793523 | 0.76 | CES2 (0.41) | ALDH1A1HPGDCYP3A4ALOX15TSHR | |
| SCHEMBL5600046 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP3A4ALOX15TSHR | |
| SCHEMBL981089 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP3A4ALOX15TSHR | |
| SCHEMBL15850522 | 0.72 | PDE2A (0.41) | ALDH1A1HPGDCYP3A4ALOX15TSHR | |
| SCHEMBL22366856 | 0.72 | GABRB3 (0.44) | ALDH1A1HPGDCYP3A4ALOX15TSHR | |
| SCHEMBL668872 | 0.72 | PDE2A (0.41) | ALDH1A1HPGDCYP3A4ALOX15TSHR | |
| SCHEMBL17351793 | 0.71 | ALDH1A1 (0.49) | ALDH1A1HPGDTDP1MAPTKDM4E | |
| SCHEMBL28061070 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HPGDCYP3A4ALOX15TSHR | |
| SCHEMBL967220 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP3A4ALOX15TSHR | |
| SCHEMBL25374080 | 0.70 | PDE2A (0.39) | ALDH1A1HPGDCYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139521-A1 | DIARYL TREHALOSE COMPOUNDS AND USES THEREOF | THE UNIV OF MONTANA (US) | 2021-05-13 | — | — | US | disclosed |
| CN-101273019-A | Novel benzimidazole and benzothiazole derivatives, method for preparing same, use thereof as drugs, pharmaceutical compositions and novel use especially as C-Met inhibitors | AVENTIS PHARMA SA (FR) | 2008-09-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139521-A1 | DIARYL TREHALOSE COMPOUNDS AND USES THEREOF | TREH, STT3B, DDOST | ALDH1A1 3190/4885HPGD 2223/4885CYP3A4 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.