Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319064 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL2362280 | 0.80 | CYP11B2 (0.47) | SMN1; SMN2GAA | |
| SCHEMBL2362323 | 0.78 | CYP11B2 (0.50) | GAAALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL2360920 | 0.77 | HCAR1 (0.50) | GAAALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL17582784 | 0.76 | RPS6KB1 (0.48) | ALDH1A1KDM4EL3MBTL1LMNAMAPT | |
| SCHEMBL21310911 | 0.76 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1PIK3CAMAPTOPRM1 | |
| SCHEMBL9982573 | 0.75 | OPRM1 (0.45) | SMN1; SMN2GAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21310910 | 0.75 | GRK6 (0.46) | ALDH1A1KDM4ECHRM1PIK3CAMEN1 | |
| SCHEMBL18779170 | 0.75 | RORC (0.42) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL4668824 | 0.74 | CHRM1 (0.70) | SMN1; SMN2GAAALOX12ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |