SCHEMBL2338566

SCHEMBL2338566

CCN([C]=O)c1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.47
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 7/20 0.41
CYP2A6 P11509 1/20 0.41
KMT2A Q03164 2/20 0.40
TSHR P16473 3/20 0.39
KDM4E B2RXH2 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 1/20 0.38
LMNA P02545 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5012205 0.86 SIGMAR1 (0.42) SIGMAR1L3MBTL1ALDH1A1CYP2A6KMT2A
SCHEMBL5010705 0.85 HTR1B (0.46) SIGMAR1ALDH1A1CYP2A6KMT2ALMNA
SCHEMBL7411647 0.84 SIGMAR1 (0.49) SIGMAR1L3MBTL1ALDH1A1CYP2A6KMT2A
SCHEMBL5010596 0.83 HTR1B (0.41) SIGMAR1ALDH1A1KMT2A
SCHEMBL5009727 0.82 HTR1B (0.40) SIGMAR1L3MBTL1ALDH1A1KMT2AKDM4E
SCHEMBL1573639 0.78 ALDH1A1 (0.41) SIGMAR1ALDH1A1CYP2A6KMT2AKDM4E
SCHEMBL1486294 0.76 SIGMAR1 (0.53) SIGMAR1ALDH1A1CYP2A6TSHRKDM4E
SCHEMBL29657743 0.75 SIGMAR1 (0.54) SIGMAR1L3MBTL1ALDH1A1CYP2A6KMT2A
SCHEMBL14461587 0.75 SIGMAR1 (0.54) SIGMAR1L3MBTL1ALDH1A1CYP2A6KMT2A
SCHEMBL517207 0.75 SIGMAR1 (0.54) SIGMAR1L3MBTL1ALDH1A1CYP2A6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX UBE INDUSTRIES, LTD. (JP) 2010-09-23 US claimed
EP-2088151-A1 GOLD COMPLEX, METHOD FOR PRODUCTION OF THE GOLD COMPLEX, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT ELEMENT USING THE GOLD COMPLEX Ube Industries, Ltd. (JP) 2009-08-12 EP claimed
EP-1814860-B1 SUBSTITUTED 5-CARBOXYAMIDE PYRAZOLES AND [1,2,4]TRIAZOLES AS ANTIVIRAL AGENTS SCHERING CORP (US) 2009-06-03 EP claimed
WO-2011099832-A2 NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME CRYSTALGENOMICS, INC. (KR) 2011-08-18 WO disclosed
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX UBE INDUSTRIES, LTD. (JP) 2010-09-23 US disclosed
EP-2088151-A1 GOLD COMPLEX, METHOD FOR PRODUCTION OF THE GOLD COMPLEX, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT ELEMENT USING THE GOLD COMPLEX Ube Industries, Ltd. (JP) 2009-08-12 EP disclosed
EP-1884513-A1 PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME Japan Tobacco, Inc. (JP) 2008-02-06 EP disclosed
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents JAPAN TOBACCO INC. (JP) 2007-02-08 US disclosed
EP-0781310-B1 MONO-N-ALKYL-QUINACRIDONE PIGMENTS CIBA GEIGY AG (CH) 1998-10-21 EP disclosed
US-5725651-A Mono-N-alkyl-quinacridone pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-03-10 US disclosed
US-5688823-A ANTILIPEMIC AGENTS, ANTIGLYCEMIC AGENTS, OBESITY, GLUCOSE TOLERANCE INSUFFICIENCY, INSULIN RESISTANCE AND DIABETIC COMPLICATIONS SANKYO COMPANY, LIMITED (JP) 1997-11-18 US disclosed
EP-0781310-A1 MONO-N-ALKYL-QUINACRIDONE PIGMENTS Ciba SC Holding AG (CH) 1997-07-02 EP disclosed
US-5578620-A TREATMENT OF DIABETES AND HYPERLIPEMIA SANKYO COMPANY, LIMITED (JP) 1996-11-26 US disclosed
WO-1996008536-A1 MONO-N-ALKYL-QUINACRIDONE PIGMENTS CIBA SPECIALTY CHEMICAL HOLDING INC. (CH) 1996-03-21 WO disclosed
EP-0678511-A2 Thiazolidine and oxazolidine derivatives, their preparation and their medical use SANKYO COMPANY LIMITED (JP) 1995-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX APOL1, UFL1, ACSL3 SIGMAR1 3437/4885L3MBTL1 2111/4885ALDH1A1 435/4885
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents PYGL, GYS2, AGL SIGMAR1 1156/4885L3MBTL1 2102/4885ALDH1A1 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.