SCHEMBL233931

SCHEMBL233931

CCO[Si](OCC)(OCC)C(CC#N)Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.41
CTSS P25774 3/20 0.36
CTSL P07711 3/20 0.36
CTSB P07858 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CTSK P43235 3/20 0.35
SLC6A2 P23975 2/20 0.35
TAAR1 Q96RJ0 2/20 0.35
SIGMAR1 Q99720 2/20 0.35
MAOA P21397 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
CYP2A6 P11509 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
PBRM1 Q86U86 1/20 0.35
TRPA1 O75762 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324755 0.87 PBRM1 (0.33) MAOBCTSSCTSLCTSBSMN1; SMN2
SCHEMBL233079 0.83 MAOB (0.42) MAOBCTSSCTSLCTSBCTSK
SCHEMBL2526801 0.80 TAAR1 (0.37) SLC6A2TAAR1SIGMAR1MAOASLC6A4
SCHEMBL2520766 0.80 ANPEP (0.43) SLC6A2TAAR1SIGMAR1MAOASLC6A4
SCHEMBL27791298 0.80 TAAR1 (0.37) SLC6A2TAAR1SIGMAR1MAOASLC6A4
SCHEMBL27689306 0.79 PPARG (0.39) SMN1; SMN2SLC6A2TAAR1SIGMAR1MAOA
SCHEMBL614548 0.77 ALDH1A1 (0.43) SMN1; SMN2SLC6A2TAAR1SIGMAR1MAOA
SCHEMBL2181964 0.75 TAAR1 (0.47) SLC6A2TAAR1SIGMAR1MAOASLC6A4
SCHEMBL28065353 0.74 SIGMAR1 (0.45) SLC6A2TAAR1SIGMAR1MAOASLC6A4
SCHEMBL339627 0.73 SIGMAR1 (0.42) SLC6A2TAAR1SIGMAR1MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
CN-114055975-A Ink jet recording method and ink jet recording apparatus 精工爱普生株式会社 2022-02-18 CN disclosed
US-10259208-B2 Three-dimensional shaped object manufacturing device, method for manufacturing three-dimensional shaped object, and three-dimensional shaped object SEIKO EPSON CORPORATION (JP) 2019-04-16 US disclosed
US-9579852-B2 Method for manufacturing three-dimensional shaped object SEIKO EPSON CORPORATION (JP) 2017-02-28 US disclosed
US-9537052-B2 Coated phosphors and light emitting devices including the same CREE, INC. (US) 2017-01-03 US disclosed
US-20160339602-A1 METHOD OF MANUFACTURING THREE-DIMENSIONAL STRUCTURE, THREE-DIMENSIONAL STRUCTURE MANUFACTURING APPARATUS, AND THREE-DIMENSIONAL STRUCTURE SEIKO EPSON CORPORATION (JP) 2016-11-24 US disclosed
US-20160263829-A1 THREE-DIMENSIONAL MODELING APPARATUS, MANUFACTURING METHOD, AND COMPUTER PROGRAM SEIKO EPSON CORPORATION (JP) 2016-09-15 US disclosed
US-9415545-B2 Method of manufacturing three-dimensional shaped object SEIKO EPSON CORPORATION (JP) 2016-08-16 US disclosed
WO-2016067584-A1 METHOD FOR MANUFACTURING THREE-DIMENSIONAL STRUCTURE, THREE-DIMENSIONAL STRUCTURE MANUFACTURING APPARATUS, AND THREE-DIMENSIONAL STRUCTURE SEIKO EPSON CORPORATION (JP) 2016-05-06 WO disclosed
US-20160107385-A1 THREE-DIMENSIONAL SHAPED OBJECT MANUFACTURING METHOD AND THREE-DIMENSIONAL SHAPED OBJECT SEIKO EPSON CORPORATION (JP) 2016-04-21 US disclosed
US-20030213732-A1 Sol-Gel monolithic column with optical window and method of making SOUTH FLORIDA, UNIVERSITY OF 2003-11-20 US disclosed
US-20030180551-A1 Conductive emulsion for preparing surface for powder coating NORTHERN ILLINOIS UNIVERSITY 2003-09-25 US disclosed
US-20030075447-A1 Sol-gel open tubular ODS columns with charged inner surface for capillary electrochromatography UNIVERSITY OF SOUTH FLORIDA 2003-04-24 US disclosed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO disclosed
WO-2002094410-A1 SOL-GEL DENDRON SEPARATION AND EXTRACTION CAPILLARY COLUMN UNIVERSITY OF SOUTH FLORIDA (US) 2002-11-28 WO disclosed
US-20020150923-A1 Sample preconcentration tubes with sol-gel surface coatings and/or sol-gel monolithic beds UNIVERSITY OF SOUTH FLORIDA, THE 2002-10-17 US disclosed
WO-2002072225-A1 HIGH EFFICIENCY SOL-GEL GAS CHROMATOGRAPHY COLUMN UNIVERSITY OF SOUTH FLORIDA (US) 2002-09-19 WO disclosed
WO-2002059591-A1 SOL-GEL OPEN TUBULAR ODS COLUMNS WITH CHARGED INNER SURFACE FOR CAPILLARY ELECTROCHROMATOGRAPHY UNIVERSITY OF SOUTH FLORIDA (US) 2002-08-01 WO disclosed
WO-2002055986-A2 SAMPLE PRECONCENTRATION TUBES WITH SOL-GEL SURFACE COATINGS AND/OR SOL-GEL MONOLITHIC BEDS UNIV SOUTH FLORIDA (US) 2002-07-18 WO disclosed
WO-2001058562-A1 SOL-GEL MONOLITHIC COLUMN WITH OPTICAL WINDOW AND METHOD OF MAKING UNIVERSITY OF SOUTH FLORIDA (US) 2001-08-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 MAOB 440/4885CTSS 3876/4885CTSL 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.