Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2347336 | 0.87 | GAA (0.70) | ALDH1A1GAAEPHX1SMN1; SMN2LMNA | |
| SCHEMBL6951894 | 0.85 | HPGD (0.77) | ALDH1A1GAASMN1; SMN2LMNAHPGD | |
| SCHEMBL14365891 | 0.81 | GAA (0.62) | ALDH1A1GAAEPHX1SMN1; SMN2LMNA | |
| SCHEMBL1030003 | 0.79 | KEAP1 (0.54) | ALDH1A1GAASMN1; SMN2LMNAKDM4E | |
| SCHEMBL2691461 | 0.78 | GAA (0.66) | ALDH1A1GAAEPHX1SMN1; SMN2LMNA | |
| SCHEMBL1514666 | 0.78 | GAA (0.57) | ALDH1A1GAAEPHX1SMN1; SMN2LMNA | |
| SCHEMBL13655375 | 0.77 | LMNA (0.84) | ALDH1A1GAAEPHX1SMN1; SMN2LMNA | |
| SCHEMBL28169793 | 0.77 | KEAP1 (0.52) | ALDH1A1SMN1; SMN2LMNAKDM4EHPGD | |
| SCHEMBL3897267 | 0.77 | SMN1; SMN2 (0.60) | ALDH1A1GAAEPHX1SMN1; SMN2LMNA | |
| SCHEMBL36169 | 0.77 | DNM1 (0.55) | ALDH1A1EPHX1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4237282-A | N-(3-DIMETHYLAMINOPROPYL)-N'-(3-MORPHOLINOPROPYL)UREA | TEXACO DEVELOPMENT CORPORATION (US) | 1980-12-02 | — | — | US | claimed |
| US-4194069-A | N-(3-DIMETHYLAMINOPROPYL)-N'-(3-MORPHOLINOPROPYL)UREA | TEXACO DEVELOPMENT CORPORATION (US) | 1980-03-18 | — | — | US | claimed |
| EP-1518872-B1 | Polyurethane catalyst compositions for improving rigid foam performance | AIR PROD & CHEM (US) | 2011-08-31 | — | — | EP | disclosed |
| EP-1468032-B1 | ALKYLAMINO OXAMIDES AS LOW ODOR NON FUGITIVE CATALYSTS FOR THE PRODUCTION OF POLYURETHANES | MOMENTIVE PERFORMANCE MAT INC (US) | 2009-10-21 | — | — | EP | disclosed |
| EP-1518872-A2 | Polyurethane catlyst compositions for improving rigid foam performance | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-1059318-B1 | Use of polyurethane catalyst compositions for improving rigid foam performance | AIR PROD & CHEM (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1468032-A1 | ALKYLAMINO OXAMIDES AS LOW ODOR, NON−FUGITIVE CATALYSTS FOR THE PRODUCTION OF POLYURETHANES | General Electric Company (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0877042-B1 | Reactive catalyst compositions for improving water blown polyurethane foam performance | AIR PROD & CHEM (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-0879837-B1 | Polyurethane catalyst compositions for improving foam perfomance | AIR PROD & CHEM (US) | 2004-07-14 | — | — | EP | disclosed |
| US-6600001-B1 | Synthesis of polyurethanes is disclosed wherein the process comprises reacting polyurethane-forming reactants in the presence of an effective amount of a catalyst comprising at least one alkylamino oxainide of the structure: | CROMPTON CORPORATION | 2003-07-29 | — | — | US | disclosed |
| WO-2003059979-A1 | ALKYLAMINO OXAMIDES AS LOW ODOR, NON-FUGITIVE CATALYSTS FOR THE PRODUCTION OF POLYURETHANES | GENERAL ELECTRIC COMPANY (US) | 2003-07-24 | — | — | WO | disclosed |
| EP-0877017-A1 | Aminomethyl pyrrolidine urea compositions for the production of polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0877016-A1 | N,N,N'-Trimethylbis (aminoethyl)-ether substituted urea compositions for the production of polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0877042-A1 | Reactive catalyst compositions for improving water blown polyurethane foam performance | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-11-11 | — | — | EP | disclosed |
| US-5824711-A | CATALYTIC REACTION OF POLYISOCYANATE AND POLYOL IN THE PRESENCE OF BLOWING AGENT FOR FORMING POLYURETHANES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |
| US-5756557-A | CATALYSTS IN THE PREPARATION OF POLYURETHANE FOAMS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| US-4237282-A | N-(3-DIMETHYLAMINOPROPYL)-N'-(3-MORPHOLINOPROPYL)UREA | TEXACO DEVELOPMENT CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4237282-A | N-(3-DIMETHYLAMINOPROPYL)-N'-(3-MORPHOLINOPROPYL)UREA | TEXACO DEVELOPMENT CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4194069-A | N-(3-DIMETHYLAMINOPROPYL)-N'-(3-MORPHOLINOPROPYL)UREA | TEXACO DEVELOPMENT CORPORATION (US) | 1980-03-18 | — | — | US | disclosed |
| US-4194069-A | N-(3-DIMETHYLAMINOPROPYL)-N'-(3-MORPHOLINOPROPYL)UREA | TEXACO DEVELOPMENT CORPORATION (US) | 1980-03-18 | — | — | US | disclosed |