Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091384 | 0.96 | EPHX1 (0.37) | EPHX1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL22519416 | 0.86 | ALDH1A1 (0.35) | EPHX1MAPK1ARG1ARG2ALDH1A1 | |
| SCHEMBL25554113 | 0.81 | ARG1 (0.35) | ARG1ARG2ALDH1A1 | |
| SCHEMBL1837224 | 0.81 | KDM4E (0.48) | EPHX1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL15602554 | 0.80 | ARG1 (0.37) | EPHX1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL21452622 | 0.80 | KDM4E (0.65) | EPHX1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL381226 | 0.80 | CYP2D6 (0.44) | EPHX1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL22299563 | 0.78 | KDM4E (0.70) | EPHX1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL13402591 | 0.78 | MEN1 (0.47) | EPHX1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL22837744 | 0.78 | KDM4E (0.70) | EPHX1KDM4EMAPK1HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014891-B2 | Reduction-triggered antibacterial sideromycins | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11014891-B2 | Reduction-triggered antibacterial sideromycins | HAMP, SLC40A1, FTH1 | EPHX1 4684/4885KDM4E 2741/4885MAPK1 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.