Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22519416 | 0.94 | ALDH1A1 (0.35) | ARG1ARG2ALDH1A1TSHRUSP2 | |
| SCHEMBL30973705 | 0.82 | CA5A (0.41) | ALDH1A1TSHRCA3CA5ACA5B | |
| SCHEMBL23397254 | 0.81 | EPHX1 (0.41) | ARG1ARG2ALDH1A1 | |
| SCHEMBL25554371 | 0.81 | PAOX (0.45) | ARG1ARG2ALDH1A1TSHRCA3 | |
| SCHEMBL19091384 | 0.81 | EPHX1 (0.37) | ARG1ARG2ALDH1A1TSHRTDP1 | |
| SCHEMBL27407746 | 0.79 | BCAT2 (0.32) | CA3CA5ACA5BTDP1 | |
| SCHEMBL25554409 | 0.78 | KMT2A (0.37) | ARG1ARG2ALDH1A1TSHRCA3 | |
| SCHEMBL21322189 | 0.77 | CYP2D6 (0.43) | ALDH1A1TSHRUSP2 | |
| SCHEMBL25554316 | 0.77 | MAOA (0.45) | ARG1ARG2TSHRTDP1 | |
| SCHEMBL17766691 | 0.76 | LMNA (0.32) | ALDH1A1CA3CA5ACA5BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159532-A1 | PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159532-A1 | PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF | PTH1R, CALCR, VDR | ARG1 4172/4885ARG2 4564/4885ALDH1A1 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.