Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25592835 | 0.86 | MEN1 (0.45) | AADATMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23420551 | 0.83 | LMNA (0.47) | MEN1KMT2ANPC1RAB9APTGS2 | |
| SCHEMBL23448671 | 0.81 | PTGER4 (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL23448681 | 0.80 | ALDH1A1 (0.47) | RAB9AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL22912925 | 0.78 | PARK7 (0.41) | AADATMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27331396 | 0.77 | ADRB2 (0.40) | AADATMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16784448 | 0.77 | KMT2A (0.57) | AADATMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23448676 | 0.74 | HDAC3 (0.44) | AADATNPC1L3MBTL1 | |
| SCHEMBL25027880 | 0.74 | PTGS2 (0.45) | AADATMEN1KMT2ANPC1RAB9A | |
| SCHEMBL22912916 | 0.73 | MEN1 (0.45) | AADATMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845996-B | Benzene ring-containing compound and application thereof | 武汉朗来科技发展有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-20230183182-A1 | COMPOUND CONTAINING BENZENE RING AND APPLICATION THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-06-15 | — | — | US | disclosed |
| US-20230183182-A1 | COMPOUND CONTAINING BENZENE RING AND APPLICATION THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-06-15 | — | — | US | disclosed |
| CN-114845996-A | Compound containing benzene ring and application thereof | 武汉朗来科技发展有限公司 | 2022-08-02 | — | — | CN | disclosed |
| WO-2021104486-A1 | COMPOUND CONTAINING BENZENE RING AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183182-A1 | COMPOUND CONTAINING BENZENE RING AND APPLICATION THEREOF | P2RX4, P2RX7, P2RX2 | AADAT 1799/4885MEN1 2798/4885KMT2A 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.