SCHEMBL2345656

SCHEMBL2345656

CC(=O)CCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.71
▸ LMNA P02545 3/20 0.71
▸ NFKB1 P19838 1/20 0.71
▸ PMP22 Q01453 1/20 0.71
▸ SLC15A2 Q16348 1/20 0.63
▸ GPR84 Q9NQS5 8/20 0.62
▸ PPARG P37231 7/20 0.62
▸ PPARD Q03181 7/20 0.62
▸ PPARA Q07869 7/20 0.62
▸ HDAC11 Q96DB2 5/20 0.62
▸ PTPN1 P18031 3/20 0.62
▸ ALDH1A1 P00352 2/20 0.62
▸ TLR2 O60603 2/20 0.62
▸ TDP1 Q9NUW8 2/20 0.62
▸ FABP4 P15090 2/20 0.62
▸ FFAR1 O14842 2/20 0.62
▸ FFAR4 Q5NUL3 2/20 0.62
▸ SLC22A6 Q4U2R8 1/20 0.62
▸ SLC22A8 Q8TCC7 1/20 0.62
▸ MEN1 O00255 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2348213 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2350916 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2348686 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL561614 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL230198 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2346285 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL24538421 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2343659 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2346452 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2
SCHEMBL2350035 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025003023-A1 METHOD FOR PRODUCING A CARBOXYLIC ACID EVONIK OPERATIONS GMBH (DE) 2025-01-02 — — WO disclosed
US-11912997-B2 RNAi agents for inhibiting expression of Superoxide Dismutase 1 (SOD1), compositions thereof, and methods of use Arrowhead Pharmaceuticals, Inc. (US) 2024-02-27 — — US disclosed
WO-2023150693-A2 NEUREGULIN-4 ANALOGS AND METHODS OF USING THEREOF IN DISEASE TREATMENT AVEXEGEN THERAPEUTICS, INC. (US) 2023-08-10 — — WO disclosed
US-20230203100-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE PEP2TANGO THERAPEUTICS INC. 2023-06-29 — — US disclosed
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 — — US disclosed
US-20180000742-A1 Pharmaceutical Composition for Oral Insulin Administration Comprising a Tablet Core and a Polyvinyl Alcohol Coating NOVO NORDISK A/S (DK) 2018-01-04 — — US disclosed
WO-2017197048-A1 ALBUMIN BINDING CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME AMUNIX OPERATING INC. (US) 2017-11-16 — — WO disclosed
US-9688737-B2 Protease stabilized acylated insulin analogues NOVO NORDISK A/S (DK) 2017-06-27 — — US disclosed
US-9688737-B2 Protease stabilized acylated insulin analogues NOVO NORDISK A/S (DK) 2017-06-27 — — US disclosed
US-20170145059-A1 Novel Amylin And Calcitonin Receptor Agonist NOVO NORDISK AS (DK) 2017-05-25 — — US disclosed
CN-1313428-C Method for producing carboxylic acid NAT INST OF ADVANCED IND SCIEN (JP) 2007-05-02 — — CN disclosed
US-7186858-B2 Method for producing carboxylic acid NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2007-03-06 — — US disclosed
US-20050215817-A1 Method for producing carboxylic acid NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2005-09-29 — — US disclosed
CN-1671642-A Process for producing carboxylic acid NAT INST OF ADV IND & TECHNOL (JP) 2005-09-21 — — CN disclosed
EP-1544190-A1 METHOD FOR PRODUCING CARBOXYLIC ACID National Institute of Advanced Industrial Science and Technology (JP) 2005-06-22 — — EP disclosed
EP-0183612-B1 BIS(PERFLUOROALKYL-2-ETHYLTHIO)-2,2-ACETALDEHYDES AND PROCESS FOR THEIR PREPARATION ELF ATOCHEM S.A. (FR) 1988-02-24 — — EP disclosed
EP-0183612-A1 Bis(perfluoroalkyl-2-ethylthio)-2,2-acetaldehydes and process for their preparation ELF ATOCHEM S.A. (FR) 1986-06-04 — — EP disclosed
EP-0057975-B1 PROCESS FOR PRODUCING POLYCONDENSATES OF OMEGA-OXYPENTADECONOIC ACID Takasago Perfumery Co., Ltd. (JP) 1985-08-14 — — EP disclosed
US-4419292-A Process for producing polycondensates of ω-oxypentadecanoic acid TAKASAGO PERFUMERY CO., LTD. (JP) 1983-12-06 — — US disclosed
EP-0057975-A1 Process for producing polycondensates of omega-oxypentadeconoic acid Takasago Perfumery Co., Ltd. (JP) 1982-08-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912997-B2 RNAi agents for inhibiting expression of Superoxide Dismutase 1 (SOD1), compositions thereof, and methods of use SOD1, SOD3, SMN1; SMN2 TSHR 4636/4885LMNA 2101/4885NFKB1 2722/4885
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR TSHR 84/4885LMNA 4542/4885NFKB1 4093/4885
US-20230203100-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE IAPP, GPR119, GIPR TSHR 443/4885LMNA 2355/4885NFKB1 3464/4885
US-20170145059-A1 Novel Amylin And Calcitonin Receptor Agonist SCTR, CALCRL, IAPP TSHR 255/4885LMNA 2777/4885NFKB1 2694/4885
US-20050215817-A1 Method for producing carboxylic acid ADH1C, HAO2, ALDH2 TSHR 2104/4885LMNA 3596/4885NFKB1 1961/4885
US-20180000742-A1 Pharmaceutical Composition for Oral Insulin Administration Comprising a Tablet Core and a Polyvinyl Alcohol Coating IAPP, SI, GPR119 TSHR 1371/4885LMNA 2023/4885NFKB1 1298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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