SCHEMBL2346339

SCHEMBL2346339

CC(=CCCOc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ALDH1A1 P00352 2/20 0.48
PPARA Q07869 1/20 0.47
TAAR1 Q96RJ0 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
KDM4E B2RXH2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HRH3 Q9Y5N1 6/20 0.44
RAB9A P51151 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3865671 0.92 L3MBTL1 (0.47) L3MBTL1ALDH1A1RAB9A
SCHEMBL2063529 0.86 LTA4H (0.45) L3MBTL1
SCHEMBL3478186 0.86 L3MBTL1 (0.56) MEN1KMT2AL3MBTL1PPARAMAOB
SCHEMBL3187272 0.86 RAB9A (0.48) MEN1KMT2AALDH1A1MAOBKDM4E
SCHEMBL196481 0.85 MTNR1A (0.51) MEN1KMT2AL3MBTL1ALDH1A1KDM4E
SCHEMBL15256 0.85 MTNR1A (0.51) MEN1KMT2AL3MBTL1ALDH1A1KDM4E
SCHEMBL3189881 0.83 MMP3 (0.54) PPARASMN1; SMN2HRH3RAB9A
SCHEMBL3849334 0.83 ALDH1A1 (0.59) ALDH1A1PPARAMAOBHRH3RAB9A
SCHEMBL9212864 0.82 HDAC1 (0.51) MEN1KMT2AALDH1A1MAOBKDM4E
SCHEMBL14993905 0.82 APP (0.43) MEN1KMT2AALDH1A1CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1944656-B1 TONER FOR DEVELOPING ELECTROSTATIC IMAGES, TONER KITS, AND IMAGE FORMATION EQUIPMENT RICOH CO LTD (JP) 2016-05-04 EP disclosed
US-9159356-B2 Non-resonant two-photon absorption recording material, non-resonant polymer two-photon absorption optical information recording medium, and recording/reproducing method FUJIFILM CORPORATION (JP) 2015-10-13 US disclosed
US-8431289-B2 Photosensitive composition for volume hologram recording, photosensitive medium for volume hologram recording and volume hologram DAI NIPPON PRINTING CO., LTD. (JP) 2013-04-30 US disclosed
US-8007976-B2 Electrostatic image developing toner, toner kit and image forming apparatus RICOH COMPANY. LTD. (JP) 2011-08-30 US disclosed
US-20100266936-A1 PHOTOSENSITIVE COMPOSITION FOR VOLUME HOLOGRAM RECORDING, PHOTOSENSITIVE MEDIUM FOR VOLUME HOLOGRAM RECORDING AND VOLUME HOLOGRAM DAI NIPPON PRINTING CO., LTD. (JP) 2010-10-21 US disclosed
US-7638250-B2 Toner, developing device, image forming apparatus, and image forming method using the toner RICOH COMPANY LIMITED (JP) 2009-12-29 US disclosed
US-20090123186-A1 ELECTROSTATIC IMAGE DEVELOPING TONER, TONER KIT AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2009-05-14 US disclosed
EP-1944656-A1 TONER FOR DEVELOPING ELECTROSTATIC IMAGES, TONER KITS, AND IMAGE FORMATION EQUIPMENT Ricoh Company, Ltd. (JP) 2008-07-16 EP disclosed
US-20070218389-A1 TONER, DEVELOPING DEVICE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD USING THE TONER RICOH COMPANY LIMITED (JP) 2007-09-20 US disclosed
EP-1248158-B1 Toner, developer, and image forming method and apparatus RICOH KK (JP) 2006-06-07 EP disclosed
US-6916587-B2 Toner, developer, and image forming method and apparatus RICOH COMPANY LIMITED (JP) 2005-07-12 US disclosed
US-20030022080-A1 Toner, developer, and image forming method and apparatus RICOH COMPANY LIMITED (JP) 2003-01-30 US disclosed
EP-1248158-A1 Toner, developer, and image forming method and apparatus Ricoh Company, Ltd. (JP) 2002-10-09 EP disclosed