SCHEMBL2063529

SCHEMBL2063529

CC(=CCCOc1ccc(O)cc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.45
NR5A1 Q13285 1/20 0.45
ESR1 P03372 1/20 0.43
ABCG2 Q9UNQ0 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
GAA P10253 1/20 0.41
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
DRD3 P35462 1/20 0.41
PPARD Q03181 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3865671 0.93 L3MBTL1 (0.47) L3MBTL1GAA
SCHEMBL17237799 0.89 NR5A1 (0.53) LTA4HNR5A1ESR1L3MBTL1GAA
SCHEMBL17237835 0.89 NR5A1 (0.53) LTA4HNR5A1ESR1L3MBTL1GAA
SCHEMBL3187272 0.87 RAB9A (0.48) PPARD
SCHEMBL3478186 0.87 L3MBTL1 (0.56) L3MBTL1GAADRD2DRD4DRD3
SCHEMBL196481 0.87 MTNR1A (0.51) L3MBTL1
SCHEMBL15256 0.87 MTNR1A (0.51) L3MBTL1
SCHEMBL2346339 0.86 MEN1 (0.48) L3MBTL1
SCHEMBL3189881 0.84 MMP3 (0.54) PPARD
SCHEMBL3849334 0.84 ALDH1A1 (0.59) PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005920-B2 Polymer composition having photoalignable group, liquid crystal alignment film formed of the polymer composition, and optical device having phase difference plate formed of the liquid crystal alignment film JNC CORPORATION (JP) 2018-06-26 US disclosed
US-9365515-B2 Oxime ester photoinitiators BASF SE (DE) 2016-06-14 US disclosed
US-20150322346-A1 POLYMER COMPOSITION HAVING PHOTOALIGNABLE GROUP, LIQUID CRYSTAL ALIGNMENT FILM FORMED OF THE POLYMER COMPOSITION, AND OPTICAL DEVICE HAVING PHASE DIFFERENCE PLATE FORMED OF THE LIQUID CRYSTAL ALIGNMENT FILM JNC CORP (JP) 2015-11-12 US disclosed
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2014-11-13 US disclosed
US-8524425-B2 Oxime ester photoinitiators BASF SE (DE) 2013-09-03 US disclosed
US-8349548-B2 Oxime ester photoinitiators BASF SE (DE) 2013-01-08 US disclosed
US-8148358-B2 Blue colour filters with enhanced contrast BASF SE (DE) 2012-04-03 US disclosed
US-20100317819-A1 SURFACE-MODIFIED NANOPARTICLES COMPRISING A CATIONIC COLORANT FOR USE IN COLOR FILTERS CIBA CORPORATION (US) 2010-12-16 US disclosed
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast CIBA CORPORATION 2010-09-09 US disclosed
US-7731791-B2 Use of pyrimido[5,4-g]pteridines as shading component in color filter colorant compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-06-08 US disclosed
US-20090293769-A1 BLUE PHTHALOCYANINE PIGMENT COMPOSITION AND ITS PREPARATION CIBA CORPORATION (US) 2009-12-03 US disclosed
US-7556843-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-07-07 US disclosed
US-7425585-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-09-16 US disclosed
US-20080206658-A1 Compositions Containing Anthraquinone Dyes HUNTSMAN INTERNATIONAL LLC (US) 2008-08-28 US disclosed
US-20080095950-A1 Compositions Containing Phthalocyanine Dyes HUNTSMAN INTERNATIONAL LLC (US) 2008-04-24 US disclosed
US-20070259278-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2007-11-08 US disclosed
US-20070249748-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2007-10-25 US disclosed
US-7247659-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-07-24 US disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US disclosed
US-20040192804-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2004-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100227199-A1 Blue Colour Filters with Enhanced Contrast NR1H4, NR1D1, NR1D2 LTA4H 3889/4885NR5A1 407/4885ESR1 203/4885
US-20100317819-A1 SURFACE-MODIFIED NANOPARTICLES COMPRISING A CATIONIC COLORANT FOR USE IN COLOR FILTERS CD63, CD59, ITGAM LTA4H 4437/4885NR5A1 4737/4885ESR1 3585/4885
US-20080095950-A1 Compositions Containing Phthalocyanine Dyes ZKSCAN2, INCENP, CRY2 LTA4H 4064/4885NR5A1 1410/4885ESR1 4525/4885
US-20140334027-A1 OXIME ESTER PHOTOINITIATORS CBR3, OR10J3, CHRM1 LTA4H 2260/4885NR5A1 746/4885ESR1 308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.