Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743711 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2CA1CA2KMT2AMEN1 | |
| SCHEMBL22691970 | 0.85 | TSHR (0.48) | SMN1; SMN2CA1CA2KMT2APOLB | |
| SCHEMBL28093622 | 0.83 | ESR1 (0.56) | CA1CA2KMT2ACES2MAPT | |
| SCHEMBL854364 | 0.83 | ESR1 (0.56) | CA1CA2KMT2ACES2MAPT | |
| SCHEMBL28554503 | 0.83 | ESR1 (0.56) | CA1CA2KMT2ACES2MAPT | |
| SCHEMBL26827 | 0.83 | ESR1 (0.56) | CA1CA2KMT2ACES2MAPT | |
| SCHEMBL670068 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2CA1CA2KMT2AMEN1 | |
| SCHEMBL19471869 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2CA1CA2KMT2AMEN1 | |
| SCHEMBL305984 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2CA1CA2KMT2AMEN1 | |
| Potassium Ion SCHEMBL1471147 | 0.82 | CA1 (0.52) | SMN1; SMN2CA1CA2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230023332-A1 | OLEAN-PHENYLACRYLAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | LUNAN PHARMACEUTICAL GROUP CORPORATION (CN) | 2023-01-26 | — | — | US | disclosed |
| CN-110256522-B | Tripterine cinnamate derivatives, and preparation method and application thereof | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |
| WO-2021104391-A1 | OLEANANE CINNAMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 鲁南制药集团股份有限公司 | 2021-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230023332-A1 | OLEAN-PHENYLACRYLAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | PAOX, ALOX12, PNMT | SMN1; SMN2 3856/4885CA1 3861/4885CA2 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.