Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472658 | 0.87 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BTLR8 | |
| SCHEMBL20219471 | 0.85 | NPSR1 (0.44) | CASP6NPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL23472301 | 0.85 | NPSR1 (0.43) | CASP6NPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL15470014 | 0.85 | TLR8 (0.48) | NPSR1S1PR2LMNASMN1; SMN2ACP1 | |
| SCHEMBL23472434 | 0.80 | CYP2D6 (0.40) | LMNASMN1; SMN2CYP2D6CYP3A4KDM4E | |
| SCHEMBL23472511 | 0.80 | CHRNB2 (0.43) | SMN1; SMN2CYP2D6CYP3A4GBA1TLR8 | |
| SCHEMBL20219428 | 0.79 | TLR7 (0.40) | NPSR1CYP2D6CYP3A4KDM4EL3MBTL1 | |
| SCHEMBL20219322 | 0.78 | CYP1A2 (0.42) | LMNASMN1; SMN2HTR1AADRA1DADRA1A | |
| SCHEMBL20219444 | 0.77 | TLR7 (0.42) | LMNASMN1; SMN2CYP3A4TLR8TLR7 | |
| SCHEMBL20219702 | 0.76 | ALDH1A1 (0.35) | L3MBTL1TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |