Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 10/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20219347 | 0.87 | HTR1A (0.50) | HTR1AADRA1DADRA1AADRA1BKDR | |
| SCHEMBL23472425 | 0.87 | CASP6 (0.41) | HTR1AADRA1DADRA1AADRA1BTLR8 | |
| SCHEMBL20219388 | 0.86 | FLT3 (0.37) | HTR1AADRA1DADRA1AADRA1BKDR | |
| SCHEMBL15470044 | 0.86 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BKDR | |
| SCHEMBL23472434 | 0.79 | CYP2D6 (0.40) | TLR8 | |
| SCHEMBL23472511 | 0.77 | CHRNB2 (0.43) | TLR8 | |
| SCHEMBL20219322 | 0.77 | CYP1A2 (0.42) | HTR1AADRA1DADRA1AADRA1BTLR8 | |
| SCHEMBL23472423 | 0.75 | MEN1 (0.45) | — | |
| SCHEMBL20219444 | 0.74 | TLR7 (0.42) | TLR8 | |
| SCHEMBL13896310 | 0.73 | MET (0.56) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |