Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20442285 | 0.74 | DDX3X (0.54) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL27104271 | 0.71 | CXCR5 (0.39) | KDM4ELMNAHTTTSHR | |
| SCHEMBL21810514 | 0.71 | SMN1; SMN2 (0.81) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL15653045 | 0.71 | LMNA (0.58) | KMT2AMEN1SNCAMAPTKDM4E | |
| SCHEMBL19501047 | 0.70 | KMT2A (0.55) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL8518685 | 0.70 | SNCA (0.75) | KMT2AMEN1SNCAMAPTKDM4E | |
| SCHEMBL19501015 | 0.69 | TGM2 (0.70) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL19491397 | 0.69 | SIRT1 (0.55) | KMT2AMEN1MAPTKDM4ELMNA | |
| SCHEMBL5532274 | 0.69 | SNCA (0.64) | KMT2AMEN1SNCAMAPTKDM4E | |
| SCHEMBL5532282 | 0.69 | SNCA (0.64) | KMT2AMEN1SNCAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339122-B2 | hTRPV1 chemical agents | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210171454-A1 | hTRPV1 CHEMICAL AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171454-A1 | hTRPV1 CHEMICAL AGENTS | TRPV1, TRPA1, TRPV4 | KMT2A 4011/4885MEN1 4488/4885SNCA 3042/4885 |
| US-11339122-B2 | hTRPV1 chemical agents | TRPV1, TRPA1, TRPV4 | KMT2A 3814/4885MEN1 4341/4885SNCA 2957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.