Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 8/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23487657 | 0.96 | LIPG (0.43) | LPLLIPGPDGFRBKDRKIF11 | |
| SCHEMBL23487532 | 0.84 | LIPG (0.54) | LPLLIPGPDGFRBKDRDGAT1 | |
| SCHEMBL23487530 | 0.83 | LPL (0.42) | LPLLIPGPDGFRBKDRDGAT1 | |
| SCHEMBL23487529 | 0.80 | LPL (0.47) | LPLLIPGPDGFRBKDR | |
| SCHEMBL23928335 | 0.77 | KIF11 (0.50) | LPLLIPGKDRKIF11FFAR1 | |
| SCHEMBL19933732 | 0.77 | DGAT1 (0.38) | LPLLIPGPDGFRBKDRDGAT1 | |
| SCHEMBL17177947 | 0.76 | LIPG (0.61) | LPLLIPGPDGFRBKDRDGAT1 | |
| SCHEMBL16009555 | 0.76 | FFAR1 (0.41) | LPLLIPGFFAR1DGAT1HIF1A | |
| SCHEMBL19794358 | 0.76 | LPL (0.39) | LPLLIPGPDGFRBKDRDGAT1 | |
| SCHEMBL19231959 | 0.76 | LPL (0.38) | LPLLIPGPDGFRBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| WO-2021110720-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MCU, IMMT, SOD1 | LPL 4205/4885LIPG 3736/4885PDGFRB 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.