Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15436242 | 0.81 | DHFR (0.46) | HTTRECQLALOX5APFEN1PIK3CA | |
| Hydrochloric Acid SCHEMBL15436256 | 0.80 | DHFR (0.45) | HTTRECQLALOX5APFEN1PIK3CA | |
| Hydrochloric Acid SCHEMBL15436275 | 0.80 | DHFR (0.45) | HTTRECQLALOX5APFEN1PIK3CA | |
| SCHEMBL23494350 | 0.75 | HTT (0.41) | HTTRECQLPIK3CADHFRHSP90AA1 | |
| SCHEMBL10917626 | 0.73 | ADORA1 (0.58) | ALOX5APPIK3CAPIK3R1MTORACHE | |
| SCHEMBL9957239 | 0.70 | PIK3C3 (0.64) | PIK3CAPIK3CDPIK3CGPI4KB | |
| SCHEMBL7915364 | 0.70 | MBOAT4 (0.47) | HTTRECQLALOX5APFEN1PIK3CA | |
| SCHEMBL9957523 | 0.70 | LMNA (0.51) | PIK3CAPIK3R1MTORKDM4EACHE | |
| SCHEMBL3642814 | 0.69 | CDK2 (0.38) | ALOX5APFEN1PIK3CAPIK3R1MTOR | |
| SCHEMBL30726498 | 0.69 | ALOX5AP (0.49) | HTTRECQLALOX5APFEN1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179591-A1 | NEW COMPOUNDS FOR USE AS A THERAPEUTICALLY ACTIVE SUBSTANCE AND IN PARTICULAR FOR USE IN THE TREATMENT OF TUMORS | ETH ZURICH (CH) | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179591-A1 | NEW COMPOUNDS FOR USE AS A THERAPEUTICALLY ACTIVE SUBSTANCE AND IN PARTICULAR FOR USE IN THE TREATMENT OF TUMORS | HNMT, MET, OGFR | HTT 2179/4885RECQL 3307/4885ALOX5AP 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.