SCHEMBL2349476

SCHEMBL2349476

CC(=Nc1cccc(C)c1C)C(C)=Nc1cccc(C)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.44
ATM Q13315 1/20 0.44
SIGMAR1 Q99720 5/20 0.40
ALDH1A1 P00352 3/20 0.39
POLB P06746 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 3/20 0.35
GRIN2D O15399 2/20 0.35
GRIN3B O60391 2/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35
GRIN2B Q13224 2/20 0.35
GRIN2C Q14957 2/20 0.35
GRIN3A Q8TCU5 2/20 0.35
MEN1 O00255 1/20 0.35
PABPC1 P11940 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7091918 0.88 TRPA1 (0.39) TRPA1ATMSIGMAR1ALDH1A1POLB
SCHEMBL13459536 0.86 TRPA1 (0.44) TRPA1ATMSIGMAR1ALDH1A1POLB
SCHEMBL22100675 0.84 NOS1 (0.45) TRPA1ATMSIGMAR1ALDH1A1POLB
SCHEMBL13459520 0.83 TRPA1 (0.41) TRPA1ATMSIGMAR1ALDH1A1POLB
SCHEMBL18379075 0.83 TRPA1 (0.41) TRPA1ATMSIGMAR1ALDH1A1POLB
SCHEMBL14816922 0.81 SIGMAR1 (0.57) SIGMAR1ALDH1A1POLBESR1ESR2
SCHEMBL29472024 0.81 SIGMAR1 (0.57) SIGMAR1ALDH1A1POLBESR1ESR2
SCHEMBL165968 0.81 SIGMAR1 (0.57) SIGMAR1ALDH1A1POLBESR1ESR2
SCHEMBL165969 0.81 SIGMAR1 (0.57) SIGMAR1ALDH1A1POLBESR1ESR2
SCHEMBL13725033 0.78 POLB (0.61) ALDH1A1POLBESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347542-A1 METHOD FOR OLIGOMERISATION IN A REACTOR COMPRISING VARIABLE-DIAMETER ZONES, INCLUDING A STEP OF RECYCLING A PRE-COOLED SOLVENT IFP Energies nouvelles (FR) 2024-04-10 EP disclosed
EP-4313918-A1 OLIGOMERISATION PROCESS COMPRISING A STEP OF RECYCLING A PRE-COOLED SOLVENT IFP Energies nouvelles (FR) 2024-02-07 EP disclosed
EP-4267290-A2 METHOD FOR OLIGOMERIZATION IN A REACTOR COMPRISING A DUAL GAS-LIQUID DISTRIBUTOR IFP Energies nouvelles (FR) 2023-11-01 EP disclosed
EP-4267293-A1 METHOD FOR OLIGOMERISATION IN A GAS/LIQUID REACTOR COMPRISING A CENTRAL DUCT IFP Energies nouvelles (FR) 2023-11-01 EP disclosed
EP-4185402-A1 OLIGOMERIZATION PROCESS IMPLEMENTING THE RECYCLING OF THE GAS HEADSPACE IFP Energies nouvelles (FR) 2023-05-31 EP disclosed
EP-4076720-A1 GAS/LIQUID OLIGOMERIZATION REACTOR COMPRISING TRANSVERSE INTERNALS IFP Energies nouvelles (FR) 2022-10-26 EP disclosed
WO-2022136012-A1 METHOD FOR OLIGOMERISATION IN A GAS/LIQUID REACTOR COMPRISING A CENTRAL DUCT IFP Energies Nouvelles (FR) 2022-06-30 WO disclosed
WO-2022136013-A2 METHOD FOR OLIGOMERIZATION IN A REACTOR COMPRISING A GAS/LIQUID DOUBLE DISTRIBUTOR IFP Energies Nouvelles (FR) 2022-06-30 WO disclosed
EP-4003942-A1 OLIGOMERIZATION PROCESS USING A RECYCLE OF GASEOUS HEADSPACE IFP Energies nouvelles (FR) 2022-06-01 EP disclosed
WO-2021185706-A1 ETHYLENE OLIGOMERISATION PLANT FOR PRODUCING ALPHA-OLEFINS IFP Energies Nouvelles (FR) 2021-09-23 WO disclosed
EP-2043991-B1 HYDROFORMYLATION PROCESS USING A COBALT-BASED CATALYST IN A NONAQUEOUS IONIC LIQUID IFP Energies Nouvelles (FR) 2011-08-31 EP disclosed
US-7781621-B2 Hydroformylation method involving a cobalt-based catalyst in a non-aqueous ionic liquid INSTITUT FRANCAIS DU PETROLE (FR) 2010-08-24 US disclosed
US-20100010270-A1 HYDROFORMYLATION METHOD INVOLVING A COBALT-BASED CATATLYST IN A NON-AQUEOUS IONIC LIQUID IFP (FR) 2010-01-14 US disclosed
EP-2043991-A1 HYDROFORMYLATION PROCESS USING A COBALT-BASED CATALYST IN A NONAQUEOUS IONIC LIQUID IFP (FR) 2009-04-08 EP disclosed
WO-2008006951-A1 HYDROFORMYLATION PROCESS USING A COBALT-BASED CATALYST IN A NONAQUEOUS IONIC LIQUID IFP (FR) 2008-01-17 WO disclosed
EP-1241156-B1 Process for the hydroformylation of olefinic unsaturated compounds in a non-aqueous ionic solvent INST FRANCAIS DU PETROLE (FR) 2004-08-18 EP disclosed
EP-1106595-B1 Improved hydroformylation process with cobalt and/or rhodium based catalysts in a biphasic medium INST FRANCAIS DU PETROLE (FR) 2004-08-11 EP disclosed
EP-1352889-A1 Hydroformylation process using a cobalt catalyst in a non-aqueous ionic liquid with catalyst recycle INSTITUT FRANCAIS DU PETROLE (FR) 2003-10-15 EP disclosed
EP-1241156-A1 Process for the hydroformylation of olefinic unsaturated compounds in a non-aqueous ionic solvent INSTITUT FRANCAIS DU PETROLE (FR) 2002-09-18 EP disclosed
EP-1106595-A1 Improved hydroformylation process with cobalt and/or rhodium based catalysts in a biphasic medium INSTITUT FRANCAIS DU PETROLE (FR) 2001-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100010270-A1 HYDROFORMYLATION METHOD INVOLVING A COBALT-BASED CATATLYST IN A NON-AQUEOUS IONIC LIQUID NUDT1, GFPT1, QPCT TRPA1 3257/4885ATM 3009/4885SIGMAR1 373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.