Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628620 | 0.95 | LMNA (0.44) | LMNAALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL26103495 | 0.95 | LMNA (0.44) | LMNAALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL18901651 | 0.95 | LMNA (0.44) | LMNAALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL31078471 | 0.95 | LMNA (0.44) | LMNAALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL278733 | 0.95 | LMNA (0.44) | LMNAALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL7717723 | 0.94 | ALDH1A1 (0.51) | LMNAALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL28421317 | 0.93 | LMNA (0.46) | LMNAALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL3499122 | 0.92 | AHR (0.42) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL6883769 | 0.87 | AHR (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11317160 | 0.87 | LMNA (0.47) | LMNAALDH1A1TDP1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754039-B2 | Targeted antimicrobial moieties | C3 JIAN, INC. (US) | 2014-06-17 | — | — | US | claimed |
| EP-3565573-B1 | PAC1 RECEPTOR AGONISTS (MAXCAPS) AND USES THEREOF | UNIV CALIFORNIA (US) | 2023-08-23 | — | — | EP | disclosed |
| US-20230052825-A1 | ANTIMICROBIAL AND ANTICANCER PEPTIDES & CONJUGATES AND COMPOSITIONS, METHODS, ARTICLES & KITS RELATING THERETO | George Mason Research Foundation, Inc. (US) | 2023-02-16 | — | — | US | disclosed |
| US-11447533-B2 | Antimicrobial and anticancer peptides and conjugates and compositions, methods, articles and kits relating thereto | George Mason Research Foundation, Inc. (US) | 2022-09-20 | — | — | US | disclosed |
| US-11219697-B2 | Osteoadsorptive fluorogenic substrate of cathepsin k for imaging osteoclast activity and migration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-11 | — | — | US | disclosed |
| US-10954271-B2 | Anti-microbial peptides | TENSIVE CONTROLS, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200215205-A1 | AN OSTEOADSORPTIVE FLUOROGENIC SUBSTRATE OF CATHEPSIN K FOR IMAGING OSTEOCLAST ACTIVITY AND MIGRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-09 | — | — | US | disclosed |
| US-20200190156-A1 | ANTIMICROBIAL AND ANTICANCER PEPTIDES & CONJUGATES AND COMPOSITIONS, METHODS, ARTICLES & KITS RELATING THERETO | George Mason Research Foundation, Inc. (US) | 2020-06-18 | — | — | US | disclosed |
| EP-3194422-B1 | ANTI-MICROBIAL PEPTIDES | TENSIVE CONTROLS INC (US) | 2020-04-29 | — | — | EP | disclosed |
| US-20200109171-A1 | ANTI-MICROBIAL PEPTIDES | ENDEVICA BIO, INC. | 2020-04-09 | — | — | US | disclosed |
| US-8889156-B2 | Calcium-binding agents induce hair growth and/or nail growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-8754039-B2 | Targeted antimicrobial moieties | C3 JIAN, INC. (US) | 2014-06-17 | — | — | US | disclosed |
| WO-2012006187-A2 | METHODS AND DEVICES FOR THE SELECTIVE DETECTION OF MICROORGANISMS | C3 JIAN, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20120003661-A1 | METHODS AND DEVICES FOR THE SELECTIVE DETECTION OF MICROORGANISMS | C3 JIAN, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-20110039762-A1 | TARGETED ANTIMICROBIAL MOIETIES | C3 JIAN, INC. (US) | 2011-02-17 | — | — | US | disclosed |
| US-20110039761-A1 | TARGETED ANTIMICROBIAL MOIETIES | C3 JIAN, INC. (US) | 2011-02-17 | — | — | US | disclosed |
| US-20110039763-A1 | TARGETED ANTIMICROBIAL MOIETIES | C3 JIAN, INC. (US) | 2011-02-17 | — | — | US | disclosed |
| US-20100316643-A1 | TARGETED ANTIMICROBIAL MOIETIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100239503-A1 | CALCIUM-BINDING AGENTS INDUCE HAIR GROWTH AND/OR NAIL GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100184683-A1 | ANTIBACTERIAL AND ANTIFUNGAL PEPTIDES | C3 JIAN, INC. (US) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11219697-B2 | Osteoadsorptive fluorogenic substrate of cathepsin k for imaging osteoclast activity and migration | CTSS, CTSK, CTSF | LMNA 2373/4885ALDH1A1 3777/4885TDP1 2004/4885 |
| US-20100239503-A1 | CALCIUM-BINDING AGENTS INDUCE HAIR GROWTH AND/OR NAIL GROWTH | S100B, S100A6, CALCB | LMNA 4426/4885ALDH1A1 3946/4885TDP1 3905/4885 |
| US-20200215205-A1 | AN OSTEOADSORPTIVE FLUOROGENIC SUBSTRATE OF CATHEPSIN K FOR IMAGING OSTEOCLAST ACTIVITY AND MIGRATION | CTSS, CTSK, CTSF | LMNA 2473/4885ALDH1A1 3743/4885TDP1 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.