Thiophanate Methyl

Thiophanate Methyl

SCHEMBL28115100

C=CCOC1=NS(=O)(=O)c2ccccc21.COC(=O)NC(S)=Nc1ccccc1N=C(S)NC(=O)OC

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.45
LMNA P02545 4/20 0.38
RAB9A P51151 1/20 0.38
HSD17B10 Q99714 3/20 0.38
HPGD P15428 2/20 0.38
ALDH1A1 P00352 2/20 0.36
GAA P10253 2/20 0.35
HTT P42858 1/20 0.35
PTPN2 P17706 1/20 0.34
PTPN1 P18031 1/20 0.34
PTPRB P23467 1/20 0.34
PKLR P30613 1/20 0.34
RHOA P61586 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophanate Methyl SCHEMBL28220504 0.80 HSD17B10 (0.51) PKMLMNARAB9AHSD17B10HPGD
Probenazol SCHEMBL8409812 0.78 PKM (0.65) PKMLMNARAB9AHSD17B10HPGD
Probenazol SCHEMBL23516 0.78 PKM (0.65) PKMLMNARAB9AHSD17B10HPGD
Probenazol SCHEMBL30425932 0.78 PKM (0.65) PKMLMNARAB9AHSD17B10HPGD
Thiophanate Methyl SCHEMBL22261863 0.72 ALDH1A1 (0.43) PKMLMNARAB9AHSD17B10HPGD
Probenazol SCHEMBL3027350 0.72 PKM (0.56) PKMLMNARAB9AHSD17B10HPGD
Thiophanate Methyl SCHEMBL28868793 0.71 ALDH1A1 (0.42) PKMLMNARAB9AHSD17B10HPGD
Isoprothiolane SCHEMBL9239101 0.67 PKM (0.44) PKMLMNARAB9AHSD17B10HPGD
Probenazol SCHEMBL28877681 0.65 PKM (0.44) PKMLMNARAB9AHSD17B10HPGD
SCHEMBL8437480 0.64 PKM (1.00) PKMLMNARAB9AHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232112-A Parasite control or extermination agent 日本曹达株式会社 2016-12-14 CN disclosed