Thiophanate Methyl

Thiophanate Methyl

SCHEMBL28220504

C=CCOC1=NS(=O)(=O)c2ccccc21.COC(=O)NC(=S)Nc1ccccc1NC(=S)NC(=O)OC

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.51
LMNA P02545 4/20 0.51
HPGD P15428 2/20 0.51
ALDH1A1 P00352 2/20 0.51
ALOX15 P16050 1/20 0.51
PKM P14618 1/20 0.46
RAB9A P51151 1/20 0.41
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36
PTPN2 P17706 1/20 0.35
PTPN1 P18031 1/20 0.35
PTPRB P23467 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PKLR P30613 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.34
RHOA P61586 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophanate Methyl SCHEMBL28115100 0.80 PKM (0.45) HSD17B10LMNAHPGDALDH1A1ALOX15
Probenazol SCHEMBL30425932 0.79 PKM (0.65) HSD17B10LMNAHPGDALDH1A1ALOX15
Probenazol SCHEMBL23516 0.79 PKM (0.65) HSD17B10LMNAHPGDALDH1A1ALOX15
Probenazol SCHEMBL8409812 0.79 PKM (0.65) HSD17B10LMNAHPGDALDH1A1ALOX15
Probenazol SCHEMBL3027350 0.73 PKM (0.56) HSD17B10LMNAHPGDALDH1A1ALOX15
Thiophanate Methyl SCHEMBL29422247 0.71 ALDH1A1 (1.00) HSD17B10LMNAHPGDALDH1A1ALOX15
Thiophanate Methyl SCHEMBL41622 0.71 ALDH1A1 (1.00) HSD17B10LMNAHPGDALDH1A1ALOX15
SCHEMBL11694355 0.71 ALDH1A1 (0.59) HSD17B10LMNAHPGDALDH1A1ALOX15
Thiophanate Methyl SCHEMBL16537027 0.70 ALDH1A1 (0.96) HSD17B10LMNAHPGDALDH1A1ALOX15
Thiophanate Methyl SCHEMBL28315984 0.70 ALDH1A1 (0.96) HSD17B10LMNAHPGDALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109169678-A Bactericide and composition thereof 侨昌现代农业有限公司 2019-01-11 CN disclosed
CN-108135171-A Agricultural or horticultural use microbicide compositions 日本曹达株式会社 2018-06-08 CN disclosed