Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23555119 | 0.86 | MCOLN2 (0.35) | MCOLN2KMT2A | |
| SCHEMBL23536479 | 0.86 | MCOLN2 (0.48) | MCOLN2KMOKMT2A | |
| SCHEMBL23536230 | 0.84 | MCOLN2 (0.39) | MCOLN2KMOKMT2A | |
| SCHEMBL23555092 | 0.83 | MCOLN2 (0.36) | MCOLN2KMOKMT2A | |
| SCHEMBL29932095 | 0.83 | LMNA (0.40) | MCOLN2KMT2A | |
| SCHEMBL23555120 | 0.82 | MCOLN2 (0.37) | MCOLN2KMOKMT2A | |
| SCHEMBL28867429 | 0.82 | MCOLN2 (0.34) | MCOLN2KMOKMT2A | |
| SCHEMBL23536204 | 0.81 | ALDH1A1 (0.41) | MCOLN2KMT2A | |
| SCHEMBL29932183 | 0.81 | ALDH1A1 (0.41) | MCOLN2KMT2A | |
| SCHEMBL23536384 | 0.81 | CRHBP (0.34) | MCOLN2KMOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |